KEGG   DISEASE: Pseudomonas aeruginosa infectionHelp
Entry
H01441                      Disease                                

Name
Pseudomonas aeruginosa infection
Description
Pseudomonas aeruginosa is a leading cause of nosocomial bloodstream infections, ranking third among gram-negative bacteria, after Escherichia coli and Klebsiella species. Intrinsic resistance has been traditionally attributed to the low permeability of cellular envelopes together with the presence of chromosomally-encoded detoxification systems such as multidrug efflux pumps or antibiotic inactivating enzymes. Some strains acquire increased resistance via the horizontal transfer of resistance determinants and mutations in chromosomal genes.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by other gamma proteobacteria
   H01441  Pseudomonas aeruginosa infection
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Other bacterial diseases
   Rickettsioses
    1C41  Bacterial infection of unspecified site
     H01441  Pseudomonas aeruginosa infection
 12 Diseases of the respiratory system
  Lung infections
   CA40  Pneumonia
    H01441  Pseudomonas aeruginosa infection
BRITE hierarchy
Pathogen
Pseudomonas aeruginosa [GN:pae pau pag pdk paep pael paes paec]
Other DBs
ICD-11: 1C41 CA40.05
ICD-10: A49.8 J15.1
MeSH: D011552
Reference
  Authors
Henrichfreise B, Wiegand I, Pfister W, Wiedemann B
  Title
Resistance mechanisms of multiresistant Pseudomonas aeruginosa strains from Germany and correlation with hypermutation.
  Journal
Antimicrob Agents Chemother 51:4062-70 (2007)
DOI:10.1128/AAC.00148-07
Reference
  Authors
Alvarez-Ortega C, Wiegand I, Olivares J, Hancock RE, Martinez JL
  Title
The intrinsic resistome of Pseudomonas aeruginosa to beta-lactams.
  Journal
Virulence 2:144-6 (2011)
DOI:10.4161/viru.2.2.15014
Reference
  Authors
El Amari EB, Chamot E, Auckenthaler R, Pechere JC, Van Delden C
  Title
Influence of previous exposure to antibiotic therapy on the susceptibility pattern of Pseudomonas aeruginosa bacteremic isolates.
  Journal
Clin Infect Dis 33:1859-64 (2001)
DOI:10.1086/324346
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