KEGG   DISEASE: Viridans group streptococcal infection
H01443                      Disease                                

Viridans group streptococcal infection
The viridans group streptococci (VGS), a heterogenous group of streptococcal species, are the predominant species of the human oral flora and commonly inhabit other areas of the upper respiratory, gastrointestinal, and female genital tracts. VGS are usually organisms of low virulence. However, VGS are a major cause of sepsis and pneumonia in neutropenic individuals, and an important cause of sepsis and meningitis in neonates. These organisms are also occasional pathogens in healthy children and adults, causing infections such as subacute endocarditis. Although VGS resistance to penicillin and the macrolide-lincosamide-streptogramin B (MLS) drugs is an evolving problem, several drugs remain uniformly active against the VGS. Thus far, VGS resistance to vancomycin, linezolid, and daptomycin remains extremely rare.
Infectious disease
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by Gram-positive bacteria
   H01443  Viridans group streptococcal infection
Streptococcus mitis
Streptococcus pseudopneumoniae [GN:std]
Streptococcus sanguinis [GN:ssa]
Streptococcus parasanguinis [GN:scf]
Streptococcus gordonii [GN:sgo]
Streptococcus constellatus [GN:scg scon scos]
Streptococcus intermedius [GN:sib siu]
Streptococcus anginosus [GN:sang sanc sans]
Streptococcus mutans [GN:smu smc smut smj]
Streptococcus sobrinus
Streptococcus salivarius [GN:ssr stf]
Streptococcus vestibularis
Streptococcus thermophilus
Streptococcus equinus
Streptococcus gallolyticus [GN:sga sgg sgt]
Streptococcus infantarius
Other DBs
ICD-10: A49.1 B95.4
MeSH: D013290
PMID:20810781 (description, pathogen)
Doern CD, Burnham CA
It's not easy being green: the viridans group streptococci, with a focus on pediatric clinical manifestations.
J Clin Microbiol 48:3829-35 (2010)
PMID:10720803 (description, pathogen)
Shenep JL
Viridans-group streptococcal infections in immunocompromised hosts.
Int J Antimicrob Agents 14:129-35 (2000)
PMID:17588233 (pathogen)
Reilly AF, Lange BJ
Infections with viridans group streptococci in children with cancer.
Pediatr Blood Cancer 49:774-80 (2007)

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