KEGG   DISEASE: Non-Hodgkin lymphoma
Entry
H02418                      Disease                                

Name
Non-Hodgkin lymphoma
  Subgroup
Chronic lymphocytic leukemia [DS:H00005]
Lymphoplasmacytic lymphoma [DS:H00011]
Hairy cell leukemia [DS:H00006]
Follicular lymphoma [DS:H01613]
Mantle cell lymphoma [DS:H01464]
Burkitt lymphoma [DS:H00008]
Peripheral T cell lymphoma [DS:H01892]
B-cell acute lymphoblastic leukemia [DS:H00001]
Mycosis fungoides [DS:H01463]
Anaplastic large-cell lymphoma [DS:H01601]
Diffuse large B-cell lymphoma, not otherwise specified [DS:H02434]
Description
Non-Hodgkin lymphoma (NHL) is one of the most common hematologic malignancies worldwide. NHL includes malignant tumors of the lymphoid tissues variously resulting from the clonal growth of B cells, T cells and natural killer cells. NHL can be broadly classified based on the type of lymphocyte involved: B lymphocyte (B cell) or T lymphocyte (T cell) and is further classified by other factors, including whether it is aggressive or indolent. Aggressive NHL is fast-growing disease. It mainly includes mantle cell lymphoma, diffuse large B-cell lymphoma, Burkitt's lymphoma, lymphoblastic lymphoma and peripheral T-cell lymphoma. On the other hand, indolent NHL is slow-growing disease. It mainly includes follicular lymphoma, cutaneous T-cell lymphoma, lymphoplasmacytic lymphoma and MALT lymphoma.
Category
Cancer
Brite
Human diseases in ICD-11 classification [BR:br08403]
 02 Neoplasms
  Neoplasms of haematopoietic or lymphoid tissues
   2B33  Malignant haematopoietic neoplasms without further specification
    H02418  Non-Hodgkin lymphoma
Drug
Bendamustine hydrochloride [DR:D07085]
Carmustine [DR:D00254]
Methotrexate sodium [DR:D02115]
Vincristine sulfate [DR:D02197]
Doxorubicin hydrochloride [DR:D01275]
Bleomycin sulfate [DR:D02177]
Rituximab [DR:D02994] (CD20-positive)
Plerixafor [DR:D08971]
Other DBs
ICD-11: 2B33.5
ICD-10: C82 C83 C84 C91
MeSH: D008228
Reference
  Authors
Crisci S, Di Francia R, Mele S, Vitale P, Ronga G, De Filippi R, Berretta M, Rossi P, Pinto A
  Title
Overview of Targeted Drugs for Mature B-Cell Non-hodgkin Lymphomas.
  Journal
Front Oncol 9:443 (2019)
DOI:10.3389/fonc.2019.00443
Reference
  Authors
Horesh N, Horowitz NA
  Title
Does gender matter in non-hodgkin lymphoma? Differences in epidemiology, clinical behavior, and therapy.
  Journal
Rambam Maimonides Med J 5:e0038 (2014)
DOI:10.5041/RMMJ.10172
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