KEGG   Equus asinus (ass): 106826327Help
Entry
106826327         CDS       T04645                                 

Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3
  KO
K04692  signal transducer and activator of transcription 3
Organism
eai  Equus asinus (ass)
Pathway
eai01521  EGFR tyrosine kinase inhibitor resistance
eai04062  Chemokine signaling pathway
eai04066  HIF-1 signaling pathway
eai04068  FoxO signaling pathway
eai04217  Necroptosis
eai04550  Signaling pathways regulating pluripotency of stem cells
eai04630  Jak-STAT signaling pathway
eai04659  Th17 cell differentiation
eai04917  Prolactin signaling pathway
eai04920  Adipocytokine signaling pathway
eai04931  Insulin resistance
eai04933  AGE-RAGE signaling pathway in diabetic complications
eai05145  Toxoplasmosis
eai05160  Hepatitis C
eai05161  Hepatitis B
eai05162  Measles
eai05163  Human cytomegalovirus infection
eai05167  Kaposi sarcoma-associated herpesvirus infection
eai05169  Epstein-Barr virus infection
eai05200  Pathways in cancer
eai05203  Viral carcinogenesis
eai05205  Proteoglycans in cancer
eai05206  MicroRNAs in cancer
eai05212  Pancreatic cancer
eai05221  Acute myeloid leukemia
eai05223  Non-small cell lung cancer
eai05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
eai05321  Inflammatory bowel disease (IBD)
Brite
KEGG Orthology (KO) [BR:eai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    106826327 (STAT3)
   04066 HIF-1 signaling pathway
    106826327 (STAT3)
   04068 FoxO signaling pathway
    106826327 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    106826327 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    106826327 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    106826327 (STAT3)
   04062 Chemokine signaling pathway
    106826327 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    106826327 (STAT3)
   04917 Prolactin signaling pathway
    106826327 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    106826327 (STAT3)
   05206 MicroRNAs in cancer
    106826327 (STAT3)
   05205 Proteoglycans in cancer
    106826327 (STAT3)
   05203 Viral carcinogenesis
    106826327 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    106826327 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    106826327 (STAT3)
   05221 Acute myeloid leukemia
    106826327 (STAT3)
   05223 Non-small cell lung cancer
    106826327 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease (IBD)
    106826327 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    106826327 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    106826327 (STAT3)
  09172 Infectious disease: viral
   05162 Measles
    106826327 (STAT3)
   05161 Hepatitis B
    106826327 (STAT3)
   05160 Hepatitis C
    106826327 (STAT3)
   05163 Human cytomegalovirus infection
    106826327 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    106826327 (STAT3)
   05169 Epstein-Barr virus infection
    106826327 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    106826327 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    106826327 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:eai03000]
    106826327 (STAT3)
Transcription factors [BR:eai03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    106826327 (STAT3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135 Syntaxin-6_N
Motif
Other DBs
NCBI-GeneID: 106826327
NCBI-ProteinID: XP_014689081
LinkDB All DBs
Position
Un
AA seq 770 aa AA seqDB search
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
NT seq 2313 nt NT seq  +upstreamnt  +downstreamnt
atggcccaatggaatcagctgcagcagctcgacacccggtacctggagcagctccatcag
ctgtacagtgacagcttcccgatggagctgcggcaatttctggccccttggattgagagt
caagattgggcgtatgcggccagcaaagaatcacatgccactttggtgtttcataatctc
ttgggtgagattgaccagcagtacagccgcttcctccaagagtcaaatgtcctctatcag
cacaatctgcgaagaatcaagcagttccttcagagcaggtatctcgagaagccaatggag
attgcccgaattgtggcccgatgcctgtgggaagagtcccgcctcctccagactgcagcc
actgcagcccagcaagggggccaggccaatcaccccaccgcggccgtggtgacggagaag
cagcagatgctggagcagcacctgcaggatgttcggaagcgagtacaggatctagaacag
aaaatgaaagtggtagagaatctccaggatgactttgatttcaactataaaaccctcaag
agtcaaggagacatgcaggatctgaatggaaacaaccagtcagtgaccaggcagaagatg
cagcagctggaacagatgcttactgcgctggaccagatgcggcgaagcatcgtgagtgag
ctggcggggcttctgtcagctatggagtatgtgcagaagactctcacggatgaagagctg
gctgactggaagaggcggcaacagattgcttgcatcggaggccctcccaacatctgccta
gatcgtctagaaaactggataacctcattagcagaatctcaacttcagacccgccaacaa
attaagaaactggaggagttgcagcagaaagtttcctataaaggagaccccatcgtacag
caccggcccatgctcgaggagagaattgtggagctgtttagaaacttaatgaaaagtgcc
tttgtggttgagcggcagccctgcatgcccatgcatcccgaccggccattagtcatcaag
accggtgtccagtttactactaaagtcagattgctggtcaaatttcccgaattaaattat
cagcttaaaattaaagtgtgcattgacaaagactccggggacgttgcagctctcagagga
tcccggaaatttaacattctgggcacaaacacaaaagtgatgaacatggaagagtccaac
aacggcagcctctctgcagagttcaaacacttgaccctgagagagcaaagatgtgggaac
gggggccgagccaattgtgacgcctccctgattgtgaccgaggagctgcacctgatcacc
tttgagactgaagtgtatcaccaaggcctcaagattgaccttgagacccactccctgcct
gttgtggtgatctccaacatctgtcagatgccaaatgcctgggcctcaatcttgtggtat
aacatgctgaccaacaaccccaagaacgtgaactttttcaccaagcccccaattggaacc
tgggatcaagtggccgaggtgctgagctggcagttctcctccaccaccaagcggggactg
agcatcgagcagttgaccacgctggcagagaaactcttaggacctggtgtgaactattca
gggtgtcagatcacgtgggctaaattttgcaaagaaaacatggctggcaagggcttctcc
ttctgggtctggctggacaatatcattgatcttgtgaaaaagtacatcctggccctctgg
aatgaagggtacataatgggctttatcagtaaggagcgggagcgggccatcttgagcacc
aagcccccaggcaccttcctgctgagattcagtgaaagcagcaaagaaggaggcgtcacc
ttcacttgggtggagaaggacatcagcggtaagactcagatccagtcagtagaaccatat
accaagcagcagctgaacaacatgtcgtttgctgagatcatcatgggctacaagatcatg
gatgccaccaatatcctggtgtctccgctggtctatctctaccccgacattccaaaggag
gaggccttcggaaagtactgtcggccagagagccaggagcatcctgaagccgacccaggt
agtgctgccccatacctgaagaccaagtttatctgtgtgacaccaacgacctgcagtaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataat
ggtgaaggtgctgagccctcagcaggagggcagtttgagtccctcacattcgacatggag
ttgacctcggagtgcgctacctcccccatgtga

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