KEGG   Equus asinus (ass): 106845016Help
Entry
106845016         CDS       T04645                                 

Gene name
HK1
Definition
(RefSeq) hexokinase 1
  KO
K00844  hexokinase [EC:2.7.1.1]
Organism
eai  Equus asinus (ass)
Pathway
eai00010  Glycolysis / Gluconeogenesis
eai00051  Fructose and mannose metabolism
eai00052  Galactose metabolism
eai00500  Starch and sucrose metabolism
eai00520  Amino sugar and nucleotide sugar metabolism
eai00524  Neomycin, kanamycin and gentamicin biosynthesis
eai01100  Metabolic pathways
eai01200  Carbon metabolism
eai04066  HIF-1 signaling pathway
eai04910  Insulin signaling pathway
eai04930  Type II diabetes mellitus
eai04973  Carbohydrate digestion and absorption
eai05230  Central carbon metabolism in cancer
Module
eai_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
eai_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:eai00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    106845016 (HK1)
   00051 Fructose and mannose metabolism
    106845016 (HK1)
   00052 Galactose metabolism
    106845016 (HK1)
   00500 Starch and sucrose metabolism
    106845016 (HK1)
   00520 Amino sugar and nucleotide sugar metabolism
    106845016 (HK1)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    106845016 (HK1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    106845016 (HK1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    106845016 (HK1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    106845016 (HK1)
 09160 Human Diseases
  09161 Cancers: Overview
   05230 Central carbon metabolism in cancer
    106845016 (HK1)
  09167 Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    106845016 (HK1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:eai04131]
    106845016 (HK1)
Enzymes [BR:eai01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     106845016 (HK1)
Membrane trafficking [BR:eai04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    106845016 (HK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Hexokinase_2 Hexokinase_1 CSD UvrD-helicase
Motif
Other DBs
NCBI-GeneID: 106845016
NCBI-ProteinID: XP_014718287
LinkDB All DBs
Position
Un
AA seq 919 aa AA seqDB search
MGQTCQRGWDAASERPIRPPLTESKIDKYLYTMRLSDETLMDIMTRFKKEMKNGLSRDFN
PTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEQNQNVHMESEIYDTPE
NIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCRQSKIDEAILITWTKRFK
ASGVEGADVVKLLEKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNA
CYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKM
VSGMYMGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVTAIEKNKEGLHNAKEIL
TRLGVEPSDDDCIAVQHVCTIVSFRSANLVAATLGAILTRLRDNKGSPRLRTTVGVDGSL
YKMHPQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIKETLAH
FSLTKDMLLEVKRRMRAEMEMGLRKQTNDRAVVKMLPSFVRSTPDGTEHGDFLALDLGGT
NFRVLLVKIRSGKKRTVEMHNKIYAIPVEIMQGTGEELFDHIVSCISDFLDYMGIKGPRM
PLGFTFSFPCKQTSLDAGILVTWTKGFKATDCVGHDVATLLRDAVKRREEFDLDVVAVVN
DTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGSEGRMCINMEWGAFGDNG
CLDDIRTHYDRLVDEYSLNPGKQRFEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETL
KTRGIFQTKYLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGA
GMAAVVDKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPQCNVSFLLSEDG
SGKGAALITAVGVRLREDS
NT seq 2760 nt NT seq  +upstreamnt  +downstreamnt
atgggacagacctgccagcgaggatgggatgcagcatctgaaaggccaatccggcccccg
cttactgaaagtaagattgacaagtatctctataccatgcggctctctgatgaaactctg
atggatatcatgactcgtttcaagaaggaaatgaagaatggcctctctcgggattttaat
ccgacagccacagtcaagatgttgccaacatttgtaaggtctattcctgatggttcagaa
aagggagatttcattgccctggatcttggtgggtcttcctttcgaattctgcgggttcaa
gtgaatcatgagcaaaaccagaatgtccacatggagtccgagatttatgacaccccggag
aacatcgtgcatggcagtggaagccagctttttgatcatgtcgccgagtgcctgggagac
ttcatggagaaaagaaaaatcaaggataagaaattacccgtgggattcacattttctttc
ccttgtcggcaatccaaaatagacgaggccatcctgatcacctggacaaagaggtttaaa
gcgagcggagtggagggagcggatgtggtgaagctgcttgaaaaagccatcaaaaagcgt
ggggattatgatgccaacattgtggctgtggtgaatgacacggtggggaccatgatgacc
tgtggctatgatgaccagcactgtgaagttgggctcatcattggcactggcaccaatgct
tgctacatggaggaactgaggcacattgacctggtggaaggtgacgagggcaggatgtgc
atcaacacggagtggggggcctttggggacgacgggtccctagaagacatccgcactgag
ttcgaccgagagatagaccggggctccctcaaccctggcaaacagctgtttgagaagatg
gtcagtggcatgtacatgggggagctggttcgactgatcctggtcaagatggccaaggaa
ggcctcttatttgaagggcggatcactccagagctgctcaccagagggaagtttaacacc
agtgatgtgacagccattgaaaagaataaggaaggcctccacaatgccaaagaaatcctg
acccgcctgggagtggagccgtctgatgacgactgtattgcagtccagcacgtgtgtacc
attgtctcatttcgctctgccaacctggtggctgcaacgctgggcgccatcttgactcgc
cttcgagataacaagggctcacccaggctgcggaccacggttggtgtcgacgggtctctt
tacaagatgcacccacagtattcccggcgtttccacaagactctgaggcgcttggtgccc
gactccgatgtacgtttcctcctctcggagagtggcagcggcaagggggccgccatggtg
accgcagtggcctatcgcctggctgagcagcaccgccagataaaggagaccctggcccac
ttcagcctcaccaaggatatgctgctggaggtgaagcggaggatgcgggccgagatggag
atggggctgaggaagcaaacgaacgaccgggccgtggtcaagatgctgccctccttcgtc
cggagcactccagatgggaccgagcatggtgacttcttggccctggatcttggaggaacg
aatttccgtgtcctactggtgaaaatccgtagtgggaaaaagagaacggtggaaatgcac
aacaagatctatgccattcctgttgaaatcatgcagggcactggggaagagctgtttgac
cacatagtctcctgcatctctgacttcctggactacatggggatcaaaggtcccagaatg
cccctgggcttcacgttctcattcccctgcaagcagacgagcttggacgcgggaattttg
gtcacctggacgaagggttttaaggcaaccgactgcgtggggcatgatgtagcgacctta
ctaagggatgcggtcaaaaggagagaggaatttgacctggacgtggtggctgtggtcaac
gacacggtgggcaccatgatgacctgtgcttatgaagagcccacctgtgaggttggactc
atcgtagggactggcagcaatgcctgctacatggaagaaatgaagaacgtcgaaatggtg
gaaggaagtgaggggcggatgtgtatcaacatggagtggggtgcctttggggacaacggc
tgtctggacgatatcagaacacactatgacagactggtggatgaatattctctaaaccct
gggaaacaaaggtttgagaagatgatcagtgggatgtacctgggtgagattgtccgcaac
atcctgatcgacttcaccaagaagggatttctcttccgagggcagatctctgagacgctg
aagacgcggggcatctttcagaccaagtatctctctcagattgagagtgaccgattagca
ctgctccaggtccgggccattctccagcagctgggcctgaacagcacctgcgacgacagt
atccttgtcaagaccgtgtgtggggtggtgtccaagagggccgcgcagctgtgtggcgcg
ggcatggctgccgtggtggataagatccgtgagaacagagggctggaccatctcaacgtg
actgtcggggtggatggaacgctctacaagcttcatccacacttctccagaatcatgcac
caaaccgtgaaggaactgtcaccacagtgtaacgtgtctttcctcctgtccgaagacggt
agtggcaagggggccgccctcatcacagcagtgggcgtacggctccgagaagacagctaa

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