Escherichia albertii: EAKF1_ch1421c
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Entry
EAKF1_ch1421c CDS
T03986
Symbol
thrA
Name
(GenBank) aspartokinase/homoserine dehydrogenase
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
eal
Escherichia albertii
Pathway
eal00260
Glycine, serine and threonine metabolism
eal00261
Monobactam biosynthesis
eal00270
Cysteine and methionine metabolism
eal00300
Lysine biosynthesis
eal01100
Metabolic pathways
eal01110
Biosynthesis of secondary metabolites
eal01120
Microbial metabolism in diverse environments
eal01230
Biosynthesis of amino acids
Module
eal_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
eal_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
eal_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
eal00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
EAKF1_ch1421c (thrA)
00270 Cysteine and methionine metabolism
EAKF1_ch1421c (thrA)
00300 Lysine biosynthesis
EAKF1_ch1421c (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
EAKF1_ch1421c (thrA)
Enzymes [BR:
eal01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
EAKF1_ch1421c (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
EAKF1_ch1421c (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
AHE59315
LinkDB
All DBs
Position
complement(1509298..1511760)
Genome browser
AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDA
LPNISDAERIFAELLTGLADAQPGFPLAQLKTFVDLEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDITESTRRIAASRIP
ADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLCADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGNPQAPGTLIGASRD
EDELPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRARISVVLITQSSSEYSISF
CVPQSDCVRAERAMQEEFYLELKEGLLEPLAVTERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVNNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
LEQLKRQQSWLKNKHIDLRVCGVANSKALLTNVHGLNLENWQEELAQAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRYAAEKSR
RKFLYDTNVGAGLPVIENLQNLLSAGDELMKFSGILSGSLSFIFGKLDEGMSFSEATALA
REMGYTEPDPRDDLSGMDVARKLLILARETGRELELSDIEIEPVLPADFNAEGDVAAFMA
NLVRLDALFAARVAKARDEGKVLRYVGNIDEDGVCRVKIAEVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcagaacgttttctgcgggtt
gccgatattctggagagcaatgccaggcaggggcaggtggcgaccgtcctctctgccccc
gccaaaatcaccaaccatctggtggcgatgattgaaaaaaccattagcggccaggatgct
ttacccaatatcagcgatgccgaacgtatttttgccgaacttctgactggactcgccgac
gctcagccgggatttccactggcgcaactgaaaactttcgtcgatctggaattcgctcaa
ataaaacatgttctgcatggcatcagcctgttagggcagtgcccggatagcattaatgcc
gcgctgatttgccgtggcgaaaaaatgtcgattgccattatggcgggtgtgctggaagcg
cgcggccacaacgttacggttatcgatccagttgaaaaactgttggcagttggtcattac
ctcgaatccaccgttgatattactgagtctacccgccgtattgccgcaagtcgcattcct
gctgaccacatggtgctgatggccggtttcaccgccggtaacgaaaaaggcgaactggtg
gtgctggggcgtaacggttctgactactctgcagccgtactggcagcttgtttatgcgcc
gattgttgtgagatctggactgacgttgatggcgtttatacctgtgacccgcgtcaggtg
cccgatgcgaggttgttgaagtcgatgtcctaccaggaagcgatggagctttcctacttc
ggcgctaaagttcttcacccccgcaccattacccccatcgcccagttccagatcccttgc
ctgataaaaaataccggaaaccctcaagcgccgggtacgctcattggcgccagtcgtgat
gaagatgagttgccggtgaagggaatttccaacctgaataacatggcgatgtttagcgtt
tccggtccgggaatgaaaggaatggtcggcatggcggcgcgcgtctttgcagcgatgtca
cgcgcccgtatttcagtggtgctgattacgcaatcgtcttccgaatacagtatcagtttc
tgcgtaccacaaagcgactgtgtgcgagctgaacgggcgatgcaggaagagttctatctt
gaactgaaagaaggtctgctggagccgctggcagtcactgaacggctggcgattatctca
gtagtgggcgatggtatgcgtacgttgcgtggcatctcagcgaaattttttgctgcgctg
gcgcgcgctaatatcaatattgttgccattgctcagggatcttccgaacgttctatctcc
gtagtggtaaataacgatgacgcaactactggtgtgcgcgttacccaccagatgctattc
aataccgatcaggttattgaagtgtttgtcattggcgtcggtggcgtgggcggggcgttg
ctggagcaactgaagcgtcagcaaagctggcttaagaacaaacatatcgacttacgcgtt
tgcggcgtcgctaactcgaaggcgttgctgactaatgtacatggcctcaatctggaaaac
tggcaggaagagcttgcacaagccaaagagccgttcaaccttgggcgcttaattcgcctg
gtgaaagaatatcatctgctgaacccggtcattgttgactgtacctccagccaggcagtg
gcggatcaatatgccgacttcctgcgcgaaggtttccacgttgttacgccgaacaaaaag
gccaacacctcgtcgatggattactaccatcagttgcgctatgcggcagaaaagtcgcgg
cgtaaattcctctacgacaccaacgtcggcgcgggattgccggttattgagaacctgcaa
aacttgctcagtgctggcgatgaattgatgaaattctccggcattctttcgggctcgctc
tcatttatcttcggtaaattagatgaaggtatgagtttctctgaggcgaccgccctggcc
cgggaaatgggctataccgaaccggacccgcgagatgatctttccggtatggatgtggcg
cgcaaattgttgattctcgcccgtgaaaccgggcgggaactggagctgtcggatatcgag
attgaacctgtgctgccagccgactttaacgcggaaggtgatgttgcggcatttatggcg
aatctggtgcgactggatgctctctttgccgcgcgcgtggcaaaggcgcgcgatgaaggc
aaagtattgcgctatgttggcaatattgatgaagatggcgtctgtcgcgtgaagattgct
gaggtcgacggtaacgatccgctgtttaaagtgaaaaacggcgaaaatgcattggccttc
tatagtcactattatcagccgctgccgctggttctccgcggttatggcgcgggcaatgac
gttacggctgctggcgtctttgccgatctgctacgcactctttcatggaagttaggagtc
tga
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