KEGG   Escherichia coli BL21(DE3): ECD_00115
Entry
ECD_00115         CDS       T00931                                 
Symbol
lpd
Name
(GenBank) dihydrolipoyl dehydrogenase; E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes; glycine cleavage system L protein; dihydrolipoamide dehydrogenase
  KO
K00382  dihydrolipoyl dehydrogenase [EC:1.8.1.4]
Organism
ebl  Escherichia coli BL21(DE3)
Pathway
ebl00010  Glycolysis / Gluconeogenesis
ebl00020  Citrate cycle (TCA cycle)
ebl00260  Glycine, serine and threonine metabolism
ebl00280  Valine, leucine and isoleucine degradation
ebl00310  Lysine degradation
ebl00380  Tryptophan metabolism
ebl00620  Pyruvate metabolism
ebl00630  Glyoxylate and dicarboxylate metabolism
ebl00640  Propanoate metabolism
ebl00785  Lipoic acid metabolism
ebl01100  Metabolic pathways
ebl01110  Biosynthesis of secondary metabolites
ebl01120  Microbial metabolism in diverse environments
ebl01200  Carbon metabolism
ebl01210  2-Oxocarboxylic acid metabolism
ebl01240  Biosynthesis of cofactors
Module
ebl_M00009  Citrate cycle (TCA cycle, Krebs cycle)
ebl_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
ebl_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
ebl_M00621  Glycine cleavage system
Brite
KEGG Orthology (KO) [BR:ebl00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    ECD_00115 (lpd)
   00020 Citrate cycle (TCA cycle)
    ECD_00115 (lpd)
   00620 Pyruvate metabolism
    ECD_00115 (lpd)
   00630 Glyoxylate and dicarboxylate metabolism
    ECD_00115 (lpd)
   00640 Propanoate metabolism
    ECD_00115 (lpd)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    ECD_00115 (lpd)
   00280 Valine, leucine and isoleucine degradation
    ECD_00115 (lpd)
   00310 Lysine degradation
    ECD_00115 (lpd)
   00380 Tryptophan metabolism
    ECD_00115 (lpd)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    ECD_00115 (lpd)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ebl04147]
    ECD_00115 (lpd)
Enzymes [BR:ebl01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.4  dihydrolipoyl dehydrogenase
     ECD_00115 (lpd)
Exosome [BR:ebl04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   ECD_00115 (lpd)
SSDB
Motif
Pfam: Pyr_redox_2 Pyr_redox_dim Pyr_redox FAD_oxidored GIDA Pyr_redox_3 FAD_binding_2 HI0933_like AlaDh_PNT_C Thi4 NAD_binding_8 FAD_binding_3 DAO Lycopene_cycl FMO-like
Other DBs
NCBI-ProteinID: ACT42016
LinkDB
Position
130717..132141
AA seq 474 aa
MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGVCLNVGCIPSKALLHVA
KVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLAGMAKGRKVKVVNGLGKFT
GANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDPRIWDSTDALELKEVPERLLV
MGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDIVKVFTKRISKKFNLMLETKVTA
VEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPNGKNLDAGKAGVEVDDRGFIRVDKQ
LRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEVIAGKKHYFDPKVIPSIAYTEPEVAWV
GLTEKEAKEKGISYETATFPWAASGRAIASDCADGMTKLIFDKESHRVIGGAIVGTNGGE
LLGEIGLAIEMGCDAEDIALTIHAHPTLHESVGLAAEVFEGSITDLPNPKAKKK
NT seq 1425 nt   +upstreamnt  +downstreamnt
atgagtactgaaatcaaaactcaggtcgtggtacttggggcaggccccgcaggttactcc
gctgccttccgttgcgctgatttaggtctggaaaccgtaatcgtagaacgttacaacacc
cttggcggtgtttgcctgaacgtcggctgtatcccttctaaagcactgctgcacgtagca
aaagttatcgaagaagccaaagcgctggctgaacacggtatcgtcttcggcgaaccgaaa
accgatatcgacaagattcgtacctggaaagagaaagtgatcaatcagctgaccggtggt
ctggctggtatggcgaaaggccgcaaagtcaaagtggtcaacggtctgggtaaattcacc
ggggctaacaccctggaagttgaaggtgagaacggcaaaaccgtgatcaacttcgacaac
gcgatcattgcagcgggttctcgcccgatccaactgccgtttattccgcatgaagatccg
cgtatctgggactccactgacgcgctggaactgaaagaagtaccagaacgcctgctggta
atgggtggcggtatcatcggtctggaaatgggcaccgtttaccacgcgctgggttcacag
attgacgtggttgaaatgttcgaccaggttatcccggcagctgacaaagacatcgttaaa
gtcttcaccaagcgtatcagcaagaaattcaacctgatgctggaaaccaaagttaccgcc
gttgaagcgaaagaagacggcatttatgtgacgatggaaggcaaaaaagcacccgctgaa
ccgcagcgttacgacgccgtgctggtagcgattggtcgtgtgccgaacggtaaaaacctc
gacgcaggcaaagcaggcgtggaagttgacgaccgtggtttcatccgcgttgacaaacag
ctgcgtaccaacgtaccgcacatctttgctatcggcgatatcgtcggtcaaccgatgctg
gcacacaaaggtgttcacgaaggtcacgttgccgctgaagttatcgccggtaagaaacac
tacttcgatccgaaagttatcccgtccatcgcctataccgaaccagaagttgcatgggtg
ggtctgactgagaaagaagcgaaagagaaaggcatcagctatgaaaccgccaccttcccg
tgggctgcttctggtcgtgctatcgcttccgactgcgcagacggtatgaccaagctgatt
ttcgacaaagaatctcaccgtgtgatcggtggtgcgattgtcggtactaacggcggcgag
ctgctgggtgaaatcggcctggcaatcgaaatgggttgtgatgctgaagacatcgcactg
accatccacgcgcacccgactctgcacgagtctgtgggcctggcggcagaagtgttcgaa
ggtagcattaccgacctgccgaacccgaaagcgaagaagaagtaa

DBGET integrated database retrieval system