Entry
Name
D-erythritol 1-phosphate dehydrogenase;
eryB (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-erythritol-1-phosphate 2-oxidoreductase
Reaction(IUBMB)
D-erythritol 1-phosphate + NADP+ = D-erythrulose 1-phosphate + NADPH + H+ [RN:
R11341 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme, characterized from the pathogenic bacterium Brucella abortus, which causes brucellosis in livestock, participates in erythritol catabolism.
History
EC 1.1.1.402 created 2016
Orthology
K21054 D-erythritol 1-phosphate dehydrogenase
Genes
URU : DSM104443_03389(eryB)
UPL : DSM104440_02897(eryB)
SMEL : SM2011_c01620(eryB)
SFD : USDA257_c12950(glpD1)
RGA : RGR602_PC00577(glpD-2)
BBAR : RHAL1_00621(glpD_1)
NOH : G5V57_07820 G5V57_19530(glpD)
RLI : RLO149_c008350(glpD1)
PMAU : CP157_02322(glpD_1)
SHUM : STHU_34040 STHU_48280
» show all
Taxonomy
Reference
Authors
Sperry JF, Robertson DC
Title
Erythritol catabolism by Brucella abortus.
Journal
Reference
Authors
Sangari FJ, Aguero J, Garcia-Lobo JM
Title
The genes for erythritol catabolism are organized as an inducible operon in Brucella abortus.
Journal
Sequence
Reference
Authors
Barbier T, Collard F, Zuniga-Ripa A, Moriyon I, Godard T, Becker J, Wittmann C, Van Schaftingen E, Letesson JJ
Title
Erythritol feeds the pentose phosphate pathway via three new isomerases leading to D-erythrose-4-phosphate in Brucella.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 1.1.1.402
LinkDB
All DBs