KEGG   ENZYME: 1.13.11.94
Entry
EC 1.13.11.94               Enzyme                                 
Name
4-vinylguaiacol dioxygenase;
Ado;
aromatic dioxygenase
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
Sysname
4-vinylguaiacol:oxygen oxidoreductase
Reaction(IUBMB)
(1) 4-vinylguaiacol + O2 = vanillin + formaldehyde [RN:R13379];
(2) 4-vinylphenol + O2 = 4-hydroxybenzaldehyde + formaldehyde [RN:R13380]
Reaction(KEGG)
R13379 R13380
Substrate
4-vinylguaiacol [CPD:C17883];
O2 [CPD:C00007];
4-vinylphenol [CPD:C05627]
Product
vanillin [CPD:C00755];
formaldehyde [CPD:C00067];
4-hydroxybenzaldehyde [CPD:C00633]
Comment
The enzyme was isolated from the bacterium Caulobacter segnis and the fungus Thermothelomyces thermophilus. It is used as an economic option in lignin degradation since it does not require a cofactor.
History
EC 1.13.11.94 created 2024
Orthology
K27873  4-vinylguaiacol dioxygenase
Genes
SMP: 10801135(SMAC4_09280)
PAN: PODANSg2204
PBEL: QC761_506740(RCO1_2)
PPSD: QC762_506740(RCO1_2)
PPSP: QC763_506740(RCO1_3)
PPSA: QC764_506740(RCO1_2)
TTT: THITE_2116474
MTM: MYCTH_2309496
MGR: MGG_06548
PPEI: PpBr36_06146
PGRI: PgNI_00982
TMN: UCRPA7_3463
SSCK: SPSK_05158
FVR: FVEG_04345
FOX: FOXG_01380 FOXG_07416
NHE: NECHADRAFT_55392 NECHADRAFT_56474 NECHADRAFT_94703
FFC: NCS54_00865900 NCS54_00887000
FKR: NCS57_00908000
FMU: J7337_006385
SAPO: SAPIO_CDS1876
PSCO: LY89DRAFT_634317
GLZ: GLAREA_03711
ANI: ANIA_07062
APUU: APUU_60751S
TRG: TRUGW13939_02052
CIM: CIMG_04860
CPW: 9696963(D8B26_008047)
PTE: PTT_01937
PTRR: 6341842(PtrM4_097110)
BZE: COCCADRAFT_94670
BSC: COCSADRAFT_153118
BOR: COCMIDRAFT_103728
AALT: CC77DRAFT_265658
ADAC: 96086485(ACET3X_006163)
ARAB: EKO05_0000100
BCOM: BAUCODRAFT_24360
NPA: UCRNP2_2174 UCRNP2_8133
RACE: JHW33_22665 JHW33_23100
SERA: Ser39006_018005
SERQ: CWC46_18005
PPOO: LW347_02060
XHY: FZ025_17485
XBN: AB3X10_13710
PFV: Psefu_2052
PFUV: NLK61_27470
PFE: PSF113_2097
PZA: HU749_019360
PFS: PFLU_4107
PVR: PverR02_20735
PMAB: U0037_20520
PFW: PF1751_v1c35450
PFF: PFLUOLIPICF718165
PBA: PSEBR_a3642
PBC: CD58_10895
PSK: U771_21525
PVK: EPZ47_18535
PCUC: PSH97_10550
MATH: THO17_13610
BUG: BC1001_4362 BC1001_4382
BPX: BUPH_00941 BUPH_00960
AVV: RvVAT039_12810
AVF: RvVAR031_32720
AVI: Avi_5950
RLU: RLEG12_08560
CSE: Cseg_1716 Cseg_1740 Cseg_1745
CAUL: KCG34_10200 KCG34_10250
SCB: SCAB_14731 SCAB_15031
SGE: DWG14_00221(lsdB) DWG14_08432
SALD: FVA74_01415
AACD: LWP59_20015
 » show all
Reference
1  [PMID:25164030]
  Authors
Furuya T, Miura M, Kino K.
  Title
A coenzyme-independent decarboxylase/oxygenase cascade for the efficient synthesis of vanillin.
  Journal
Chembiochem 15:2248-54 (2014)
DOI:10.1002/cbic.201402215
  Sequence
[cse:Cseg_1716 Cseg_1740 Cseg_1745]
Reference
2  [PMID:30376327]
  Authors
Ni J, Wu YT, Tao F, Peng Y, Xu P.
  Title
A Coenzyme-Free Biocatalyst for the Value-Added Utilization of Lignin-Derived Aromatics.
  Journal
J Am Chem Soc 140:16001-16005 (2018)
DOI:10.1021/jacs.8b08177
  Sequence
[mtm:MYCTH_2309496]
Other DBs
ExplorEnz - The Enzyme Database: 1.13.11.94
IUBMB Enzyme Nomenclature: 1.13.11.94
ExPASy - ENZYME nomenclature database: 1.13.11.94
BRENDA, the Enzyme Database: 1.13.11.94
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