Entry |
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Name |
4-chlorophenylacetate 3,4-dioxygenase
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Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
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Sysname |
4-chlorophenylacetate,NADH:oxygen oxidoreductase (3,4-hydroxylating, dechlorinating)
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Reaction(IUBMB) |
4-chlorophenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + chloride + NAD+ [RN: R03306]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
A system, containing a reductase and an iron-sulfur oxygenase, and no independent ferredoxin. Requires Fe2+. Also acts on 4-bromophenyl acetate.
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History |
EC 1.14.12.9 created 1989 as EC 1.13.99.4, transferred 1992 to EC 1.14.12.9
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Pathway |
ec01120 | Microbial metabolism in diverse environments |
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Reference |
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Authors |
Markus A, Krekel D, Lingens F. |
Title |
Purification and some properties of component A of the 4-chlorophenylacetate 3,4-dioxygenase from Pseudomonas species strain CBS. |
Journal |
J Biol Chem 261:12883-8 (1986) |
Other DBs |
ExPASy - ENZYME nomenclature database: | 1.14.12.9 |
UM-BBD (Biocatalysis/Biodegradation Database): | 1.14.12.9 |
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LinkDB |
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