| Entry |
|
|---|
| Name |
4-chlorophenylacetate 3,4-dioxygenase
|
|---|
| Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
|
|---|
| Sysname |
4-chlorophenylacetate,NADH:oxygen oxidoreductase (3,4-hydroxylating, dechlorinating)
|
|---|
| Reaction(IUBMB) |
4-chlorophenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + chloride + NAD+ [RN: R03306]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
|
|---|
| Product |
|
|---|
| Comment |
A system, containing a reductase and an iron-sulfur oxygenase, and no independent ferredoxin. Requires Fe2+. Also acts on 4-bromophenyl acetate.
|
|---|
| History |
EC 1.14.12.9 created 1989 as EC 1.13.99.4, transferred 1992 to EC 1.14.12.9
|
|---|
| Pathway |
| ec01120 | Microbial metabolism in diverse environments |
|
|---|
| Reference |
|
|---|
| Authors |
Markus A, Krekel D, Lingens F. |
|---|
| Title |
Purification and some properties of component A of the 4-chlorophenylacetate 3,4-dioxygenase from Pseudomonas species strain CBS. |
|---|
| Journal |
J Biol Chem 261:12883-8 (1986) |
|---|
| Other DBs |
| ExPASy - ENZYME nomenclature database: | 1.14.12.9 |
| UM-BBD (Biocatalysis/Biodegradation Database): | 1.14.12.9 |
|
|---|
| LinkDB |
|
|---|
