| Entry |
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| Name |
2,4-dichlorophenol 6-monooxygenase;
2,4-dichlorophenol hydroxylase;
2,4-dichlorophenol monooxygenase
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| Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
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| Sysname |
2,4-dichlorophenol,NADPH:oxygen oxidoreductase (6-hydroxylating)
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| Reaction(IUBMB) |
2,4-dichlorophenol + NADPH + H+ + O2 = 3,5-dichlorocatechol + NADP+ + H2O [RN: R03997]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
A flavoprotein (FAD). Also acts, more slowly, on 4-chlorophenol and 4-chloro-2-methylphenol; NADH can act instead of NADPH, but more slowly.
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| History |
EC 1.14.13.20 created 1983
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| Pathway |
| ec00361 | Chlorocyclohexane and chlorobenzene degradation |
| ec01120 | Microbial metabolism in diverse environments |
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| Orthology |
| K10676 | 2,4-dichlorophenol 6-monooxygenase |
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| Genes |
» show all
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| Reference |
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| Authors |
Beadle CA, Smith AR. |
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| Title |
The purification and properties of 2,4-dichlorophenol hydroxylase from a strain of Acinetobacter species. |
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| Journal |
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| Other DBs |
| UM-BBD (Biocatalysis/Biodegradation Database): | 1.14.13.20 |
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| LinkDB |
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