| Entry |
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| Name |
salicyloyl-CoA 5-hydroxylase;
sdgC (gene name)
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| Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
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| Sysname |
salicyloyl-CoA,NADH:oxygen oxidoreductase (5-hydroxylating)
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| Reaction(IUBMB) |
2-hydroxybenzoyl-CoA + NADH + H+ + O2 = gentisyl-CoA + NAD+ + H2O [RN: R11056]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzyme, characterized from the bacterium Streptomyces sp. WA46, participates in a pathway for salicylate degradation. cf. EC 1.14.13.172, salicylate 5-hydroxylase.
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| History |
EC 1.14.13.209 created 2015
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| Orthology |
| K21684 | salicyloyl-CoA 5-hydroxylase |
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| Genes |
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| Reference |
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| Authors |
Ishiyama D, Vujaklija D, Davies J |
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| Title |
Novel pathway of salicylate degradation by Streptomyces sp. strain WA46. |
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| Journal |
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| Sequence |
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| Other DBs |
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| LinkDB |
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