| Entry |
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| Name |
4-aminobenzoate 1-monooxygenase;
4-aminobenzoate hydroxylase;
4-aminobenzoate monooxygenase
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| Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
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| Sysname |
4-aminobenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating)
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| Reaction(IUBMB) |
4-aminobenzoate + NAD(P)H + 2 H+ + O2 = 4-hydroxyaniline + NAD(P)+ + H2O + CO2 [RN: R02561 R02562]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
A flavoprotein (FAD). Acts on anthranilate and 4-aminosalicylate but not on salicylate (cf. EC 1.14.13.1 salicylate 1-monooxygenase).
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| History |
EC 1.14.13.27 created 1989
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| Pathway |
| ec01120 | Microbial metabolism in diverse environments |
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| Reference |
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| Authors |
Tsuji H, Ogawa T, Bando N, Sasaoka K. |
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| Title |
Purification and properties of 4-aminobenzoate hydroxylase, a new monooxygenase from Agaricus bisporus. |
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| Journal |
J Biol Chem 261:13203-9 (1986) |
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| Other DBs |
| UM-BBD (Biocatalysis/Biodegradation Database): | 1.14.13.27 |
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| LinkDB |
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