| Entry |
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| Name |
questin monooxygenase;
questin oxygenase
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| Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
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| Sysname |
questin,NADPH:oxygen oxidoreductase (hydroxylating, anthraquinone-ring-opening)
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| Reaction(IUBMB) |
questin + NADPH + H+ + O2 = demethylsulochrin + NADP+ [RN: R02417]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzyme cleaves the anthraquinone ring of questin to form a benzophenone. Involved in the biosynthesis of the seco-anthraquinone (+)-geodin.
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| History |
EC 1.14.13.43 created 1992
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| Reference |
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| Authors |
Fujii I, Ebizuka Y, Sankawa U. |
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| Title |
A novel anthraquinone ring cleavage enzyme from Aspergillus terreus. |
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| Journal |
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| Other DBs |
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| LinkDB |
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