Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy

resorcinol,FADH2:oxygen oxidoreductase (4-hydroxylating)

resorcinol + FADH2 + O2 = hydroxyquinol + FAD + H2O [RN:R11348]

R11348
Reaction

resorcinol [CPD:C01751];
FADH2 [CPD:C01352];
O2 [CPD:C00007]

The enzyme, characterized from the bacterium Rhizobium sp. strain MTP-10005, uses FADH2 as a substrate rather than a cofactor. FADH2 is provided by a dedicated EC 1.5.1.36, flavin reductase (NADH). The enzyme participates in the degradation of gamma-resorcylate and resorcinol. cf. EC 1.14.13.220, resorcinol 4-hydroxylase (NADH), and EC 1.14.13.219, resorcinol 4-hydroxylase (NADPH).

EC 1.14.14.27 created 2016

1  [PMID:1280]

Ohta Y, Ribbons DW

Bacterial metabolism of resorcinylic compounds: purification and properties of orcinol hydroxylase and resorcinol hydroxylase from Pseudomonas putida ORC.

Eur J Biochem 61:259-69 (1976)
DOI:10.1111/j.1432-1033.1976.tb10019.x

2  [PMID:17158677]

Yoshida M, Oikawa T, Obata H, Abe K, Mihara H, Esaki N

Biochemical and genetic analysis of the gamma-resorcylate (2,6-dihydroxybenzoate) catabolic pathway in Rhizobium sp. strain MTP-10005: identification and functional analysis of its gene cluster.

J Bacteriol 189:1573-81 (2007)
DOI:10.1128/JB.01675-06

[ag:BAF44522]