KEGG   ENZYME: 1.17.98.3
Entry
EC 1.17.98.3                Enzyme                                 

Name
formate dehydrogenase (coenzyme F420);
coenzyme F420 reducing formate dehydrogenase;
coenzyme F420-dependent formate dehydrogenase
Class
Oxidoreductases;
Acting on CH or CH2 groups;
With other, known, physiological acceptors
Sysname
formate:coenzyme-F420 oxidoreductase
Reaction(IUBMB)
formate + oxidized coenzyme F420 = CO2 + reduced coenzyme F420 [RN:R10797]
Reaction(KEGG)
R10797
Substrate
formate [CPD:C00058];
oxidized coenzyme F420 [CPD:C00876]
Product
CO2 [CPD:C00011];
reduced coenzyme F420 [CPD:C01080]
Comment
The enzyme, characterized from methanogenic archaea, is involved in formate-dependent H2 production. It contains noncovalently bound FAD [1].
History
EC 1.17.98.3 created 2014 as EC 1.2.99.9, transferred 2017 to EC 1.17.98.3
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K00125  formate dehydrogenase (coenzyme F420) beta subunit
K22516  formate dehydrogenase (coenzyme F420) alpha subunit
Genes
VNA: PN96_21155
VEJ: VEJY3_20411
PGB: H744_1c0419
PSH: Psest_3905
PSTU: UIB01_19765
PCH: EY04_14750
PSED: DM292_16890
GNI: GNIT_2862
TMB: Thimo_0255
CHIZ: HQ393_09255
SLAC: SKTS_06260
CCO: CCC13826_0200(fdhH)
CCOC: CCON33237_0536(fdhH)
CGRA: CGRAC_1361(fdhH)
CPIN: CPIN18020_0262(fdhH)
CGEO: CGEO_1649(fdhH)
AHS: AHALO_1025(fdhH)
AMAR: AMRN_1963(fdhH)
ACAA: ACAN_2017(fdhH)
SULJ: SJPD1_1032
GEO: Geob_0149
PCA: Pcar_2701
DMA: DMR_01940
DGG: DGI_1052(floxC)
DAS: Daes_0781
DPI: BN4_11862
DBA: Dbac_2346
DRT: Dret_0419
DSF: UWK_03159
DAL: Dalk_5062
DAT: HRM2_11880(fdhA3) HRM2_14370(fdhA4) HRM2_22740(fdhB6)
DBR: Deba_2134
BLAG: BLTE_14910
EFS: EFS1_1216
ENE: ENT_08450
CSQ: CSCA_0253
RCH: RUM_11000
RUM: CK1_05080
SWO: Swol_0400
SALQ: SYNTR_0266
DSY: DSY1990
DHD: Dhaf_3153
PTH: PTH_1407(RnfC)
DAU: Daud_0567
SGY: Sgly_1898
HMO: HM1_2010
CTHM: CFE_1626
CHY: CHY_0932
ADG: Adeg_1331
SFI: SFUL_466
MMP: MMP0138(fdhA) MMP0139(fdhB) MMP1297(fdhB) MMP1298(fdhA)
MMAK: MMKA1_01430(fdhA) MMKA1_01440(fdhB) MMKA1_15220(fdhB) MMKA1_15230(fdhA)
MMAO: MMOS7_01690(fdhA) MMOS7_01700(fdhB) MMOS7_14040(fdhB) MMOS7_14050(fdhA)
MMAD: MMJJ_09460 MMJJ_09470(fdhF_2) MMJJ_15440(fdhA2) MMJJ_15460(fdhB1)
MMG: MTBMA_c15220(fdhB) MTBMA_c15230(fdhA2)
MWO: MWSIV6_0697(fdhA5) MWSIV6_0698(fdhB1) MWSIV6_1531(fdhB3) MWSIV6_1532
MST: Msp_0639(fdhB) Msp_0640(fdhA)
MRU: mru_0333(fdhA1) mru_0334(fdhB1) mru_2074(fdhA2) mru_2075(fdhB2)
MEB: Abm4_0131(fdhA) Abm4_0132(fdhB) Abm4_0854(fdhB2) Abm4_0855(fdhA2)
MMIL: sm9_1349(flpB) sm9_1350(flpA) sm9_2182(fdhB) sm9_2183(fdhA)
METH: MBMB1_0103(fdhB) MBMB1_0104(fdhA)
MFC: BRM9_0167(fdhB) BRM9_0168(fdhA)
MFI: DSM1535_1485(fdhB) DSM1535_1486(fdhA)
MCUB: MCBB_2028(fdhA) MCBB_2029(fdhB1) MCBB_2031(fdhB3)
FPL: Ferp_0094
TAC: Ta0045
TVO: TVG0003442(TVG0003442)
FAI: FAD_1471
PYN: PNA2_1925
PYS: Py04_1234
TKO: TK2076
TGA: TGAM_0065(mhy2A) TGAM_0249(fdh1A) TGAM_0631(fdhA)
TSI: TSIB_0067
PPAC: PAP_03230
METM: MSMTP_1177
MCJ: MCON_2237(fdhA)
MBG: BN140_0841(fdhB) BN140_0842(fdhA) BN140_1327(fdhA1) BN140_1328(fdhB1) BN140_1329(fdhA2) BN140_1330(fdhB2) BN140_2197(fdhB3) BN140_2198(fdhA3)
MEMA: MMAB1_1105(fdhB) MMAB1_1106(fdhA) MMAB1_1689(fdhA) MMAB1_1690(fdhB) MMAB1_2913(fdhB) MMAB1_2914(fdhA)
MPD: MCP_1569(fdhB-1) MCP_1570(fdhA-1) MCP_2406(fdhB-2) MCP_2407(fdhA-2)
MEZ: Mtc_2124(fdhB) Mtc_2125(fdhA)
RCI: RCIX1628(fdhA-1) RCIX1630(fdhB-1) RCIX2372(fdhB-2) RCIX2373(fdhA-2) RCIX2376(fdhB-3) RCIX2378(fdhA-3) RRC251(fdhA-4) RRC252(fdhB-4)
HHB: Hhub_2705(fdhA)
HALH: HTSR_1736(fdhA) HTSR_1740(fdhA2)
HHSR: HSR6_1802(fdoG2) HSR6_1806(fdoG3)
HHI: HAH_5041(fdhA)
NMO: Nmlp_2714(fdhA)
HLA: Hlac_1238
HALQ: Hrr1229_013155(fdhF)
HALU: HUG12_20610(fdhF)
HDF: AArcSl_0465(fdoG) AArcSl_1489(fdoG2)
HTU: Htur_0685
HALY: HYG82_00570(fdhF)
IHO: Igni_1101
IIS: EYM_07315
MSE: Msed_1457
AHO: Ahos_2012
STEP: IC006_0501
VDI: Vdis_2449
TPE: Tpen_0190
PSYT: DSAG12_02784(fdhB_1) DSAG12_03719(fdhB_2)
 » show all
Reference
1  [PMID:6874636]
  Authors
Schauer NL, Ferry JG
  Title
FAD requirement for the reduction of coenzyme F420 by formate dehydrogenase from  Methanobacterium formicicum.
  Journal
J Bacteriol 155:467-72 (1983)
DOI:10.1128/JB.155.2.467-472.1983
Reference
2  [PMID:3944055]
  Authors
Schauer NL, Ferry JG
  Title
Composition of the coenzyme F420-dependent formate dehydrogenase from Methanobacterium formicicum.
  Journal
J Bacteriol 165:405-11 (1986)
DOI:10.1128/JB.165.2.405-411.1986
Reference
3  [PMID:18791018]
  Authors
Lupa B, Hendrickson EL, Leigh JA, Whitman WB
  Title
Formate-dependent H2 production by the mesophilic methanogen Methanococcus maripaludis.
  Journal
Appl Environ Microbiol 74:6584-90 (2008)
DOI:10.1128/AEM.01455-08
Other DBs
ExplorEnz - The Enzyme Database: 1.17.98.3
IUBMB Enzyme Nomenclature: 1.17.98.3
ExPASy - ENZYME nomenclature database: 1.17.98.3
BRENDA, the Enzyme Database: 1.17.98.3
LinkDB

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