| Entry |
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| Name |
isopyridoxal dehydrogenase (5-pyridoxate-forming)
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| Class |
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
isopyridoxal:NAD+ oxidoreductase (5-pyridoxate-forming)
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| Reaction(IUBMB) |
isopyridoxal + NAD+ + H2O = 5-pyridoxate + NADH + H+ [RN: R12265]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzyme, characterized from the bacterium Arthrobacter sp. Cr-7, participates in the degradation of pyridoxine. The enzyme also catalyses the activity of EC 1.1.1.416, isopyridoxal dehydrogenase (5-pyridoxolactone-forming).
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| History |
EC 1.2.1.102 created 2018
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| Pathway |
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| Reference |
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| Authors |
Lee YC, Nelson MJ, Snell EE. |
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| Title |
Enzymes of vitamin B6 degradation. Purification and properties of isopyridoxal dehydrogenase and 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylic-acid dehydrogenase. |
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| Journal |
J Biol Chem 261:15106-11 (1986) |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 1.2.1.102 |
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| LinkDB |
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