| Entry |
|
|---|
| Name |
aldehyde dehydrogenase (quinone);
aldehyde dehydrogenase (acceptor)
|
|---|
| Class |
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With a quinone or similar compound as acceptor
|
|---|
| Sysname |
aldehyde:quinone oxidoreductase
|
|---|
| Reaction(IUBMB) |
an aldehyde + a quinone + H2O = a carboxylate + a quinol [RN: R10911]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
|
|---|
| Product |
|
|---|
| Comment |
Wide specificity; acts on straight-chain aldehydes up to C10, aromatic aldehydes, glyoxylate and glyceraldehyde. The enzymes contains a PQQ cofactor and multiple hemes that deliver the electrons to the membrane quinone pool.
|
|---|
| History |
EC 1.2.5.2 created 1983 as EC 1.2.99.3, modified 1989, transferred 2015 to EC 1.2.5.2
|
|---|
| Pathway |
|
|---|
| Reference |
1 |
|---|
| Authors |
Ameyama, M. and Adachi, O. |
|---|
| Title |
Aldehyde dehydrogenase from acetic acid bacteria, membrane-bound. |
|---|
| Journal |
Methods Enzymol 89:491-497 (1982) |
|---|
| Reference |
2 |
|---|
| Authors |
Ameyama, M., Osada, K., Shinagawa, E., Matsushita, K. and Adachi, O. |
|---|
| Title |
Purification and characterization of aldehyde dehydrogenase of Acetobacter aceti. |
|---|
| Journal |
Agric Biol Chem 45:1189-1890 (1981) |
|---|
| Reference |
|
|---|
| Authors |
Patel RN, Hou CT, Derelanko P, Felix A. |
|---|
| Title |
Purification and properties of a heme-containing aldehyde dehydrogenase from Methylosinus trichosporium. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Gomez-Manzo S, Chavez-Pacheco JL, Contreras-Zentella M, Sosa-Torres ME, Arreguin-Espinosa R, Perez de la Mora M, Membrillo-Hernandez J, Escamilla JE |
|---|
| Title |
Molecular and catalytic properties of the aldehyde dehydrogenase of Gluconacetobacter diazotrophicus, a quinoheme protein containing pyrroloquinoline quinone, cytochrome b, and cytochrome c. |
|---|
| Journal |
|
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.2.5.2 |
| ExPASy - ENZYME nomenclature database: | 1.2.5.2 |
| BRENDA, the Enzyme Database: | 1.2.5.2 |
|
|---|
| LinkDB |
|
|---|
