KEGG   ENZYME: 1.21.3.4
Entry
EC 1.21.3.4                 Enzyme                                 

Name
sulochrin oxidase [(+)-bisdechlorogeodin-forming];
sulochrin oxidase
Class
Oxidoreductases;
Catalysing the reaction X-H + Y-H = X-Y;
With oxygen as acceptor
Sysname
sulochrin:oxygen oxidoreductase (cyclizing, (+)-specific)
Reaction(IUBMB)
2 sulochrin + O2 = 2 (+)-bisdechlorogeodin + 2 H2O [RN:R00060]
Reaction(KEGG)
R00060
Substrate
sulochrin [CPD:C00495];
O2 [CPD:C00007]
Product
(+)-bisdechlorogeodin [CPD:C03036];
H2O [CPD:C00001]
Comment
Also acts on several diphenols and phenylenediamines, but has low affinity for these substrates. Involved in the biosynthesis of mould metabolites related to the antibiotic griseofulvin.
History
EC 1.21.3.4 created 1986 as EC 1.10.3.7, transferred 2002 to EC 1.21.3.4
Reference
1  [PMID:7049104]
  Authors
Nordlov H, Gatenbeck S.
  Title
Enzymatic synthesis of (+)- and (-)-bisdechlorogeodin with sulochrin oxidase from Penicillium frequentans and Oospora sulphurea-ochracea.
  Journal
Arch Microbiol 131:208-11 (1982)
DOI:10.1007/bf00405880
Other DBs
ExplorEnz - The Enzyme Database: 1.21.3.4
IUBMB Enzyme Nomenclature: 1.21.3.4
ExPASy - ENZYME nomenclature database: 1.21.3.4
BRENDA, the Enzyme Database: 1.21.3.4
CAS: 82469-87-2
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