KEGG   ENZYME: 1.3.1.111
Entry
EC 1.3.1.111                Enzyme                                 

Name
geranylgeranyl-bacteriochlorophyllide a reductase;
geranylgeranyl-bacteriopheophytin reductase;
bchP (gene name)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
bacteriochlorophyll-a:NADP+ oxidoreductase (geranylgeranyl-reducing)
Reaction(IUBMB)
bacteriochlorophyll a + 3 NADP+ = geranylgeranyl bacteriochlorophyllide a + 3 NADPH + 3 H+ [RN:R11226]
Reaction(KEGG)
R11226;
(other) R11518
Substrate
bacteriochlorophyll a [CPD:C11242];
NADP+ [CPD:C00006]
Product
geranylgeranyl bacteriochlorophyllide a [CPD:C21217];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme catalyses the successive reduction of the geranylgeraniol esterifying group to phytol, reducing three out of four double bonds, and transforming geranylgeranyl bacteriochlorophyllide a via dihydrogeranylgeranyl bacteriochlorophyllide a and tetrahydrogeranylgeranyl bacteriochlorophyllide a to bacteriochlorophyll a. The enzyme can also accept the pheophytin derivative geranylgeranyl bacteriopheophytin, converting it to bacteriopheophytin a.
History
EC 1.3.1.111 created 2016
Pathway
ec00860  Porphyrin and chlorophyll metabolism
ec01110  Biosynthesis of secondary metabolites
Orthology
K10960  geranylgeranyl diphosphate/geranylgeranyl-bacteriochlorophyllide a reductase
Genes
SLAL: 111647855
ATH: AT1G74470
ALY: 9325042
CRB: 17894023
CSAT: 104702172 104713087 104751317
EUS: EUTSA_v10018504mg
BRP: 103831923 103852907
BNA: 106354395 106381375 106405742 106430268
BOE: 106300254 106327384
RSZ: 108816026 108816096 108818449
THJ: 104813881
LJA: Lj2g3v2971720.1(Lj2g3v2971720.1)
PMUM: 103338504
PXB: 103931434
CMO: 103493994(GGPR)
MESC: 110599909
QSU: 111998707
NNU: 104602940
DOSA: Os01t0265000-00(Os01g0265000) Os02t0744900-01(Os02g0744900)
OBR: 102704037
ATS: 109757451(LOC109757451) 109766926(LOC109766926)
ZMA: 100283007(pco077228) 103649981
PEQ: 110032603
AOF: 109834138
ATR: 110007115
APRO: F751_0551
OLU: OSTLU_119498(ggh)
SMIN: v1.2.003912.t1(symbB.v1.2.003912.t1) v1.2.012563.t1(symbB.v1.2.012563.t1) v1.2.013265.t1(symbB.v1.2.013265.t1) v1.2.013265.t2(symbB.v1.2.013265.t2) v1.2.021307.t1(symbB.v1.2.021307.t1) v1.2.025959.t1(symbB.v1.2.025959.t1)
HHA: Hhal_1602
HHK: HH1059_06380(bchP)
LIM: L103DPR2_01008(kmo)
MPT: Mpe_A2779
RGE: RGE_33390(bchP)
SULR: B649_08370
SUN: SUN_1446
NAM: NAMH_1575
BRA: BRADO1632(bchP)
BBT: BBta_6424(bchP)
BRS: S23_19290(bchP)
AOL: S58_59050
BRO: BRAD285_5768(bchP)
RPA: RPA1532(bchP)
RPB: RPB_3990
RPC: RPC_1304
RPD: RPD_3745
RPE: RPE_1338
RPT: Rpal_1721
MEA: Mex_1p5279(bchP)
MDI: METDI5879(bchP)
MEX: Mext_4822
MCH: Mchl_5289
MPO: Mpop_5367
MET: M446_3712
MOR: MOC_2259(bchP)
META: Y590_24640
MAQU: Maq22A_c01650(fixC)
MSL: Msil_2063
BBAR: RHAL1_00139(bchP)
RVA: Rvan_1004
BVR: BVIR_564
BLAG: BLTE_02000(bchP)
RSP: RSP_0277(bchP)
RCP: RCAP_rcc00673(bchP)
JAN: Jann_0167(bchP)
RDE: RD1_0146(bchP)
RLI: RLO149_p940650(bchP)
DSH: Dshi_3528(bchP)
PTP: RCA23_c29730(bchP)
RSU: NHU_00205
RHC: RGUI_1992
MALU: KU6B_16760
SPHI: TS85_23035
SSAN: NX02_18305
BLAS: BSY18_2715
AMV: ACMV_18910(bchP)
RRU: Rru_A0629
RRF: F11_03225
RCE: RC1_2080(bchP)
RPM: RSPPHO_00051(bchP)
CPAT: CLPA_c27280(cbrA)
CPAE: CPAST_c27280(cbrA)
AOE: Clos_1275
CSS: Cst_c14230(cbrA)
CSD: Clst_1373
DSY: DSY3068
DHD: Dhaf_4237
MBJ: KQ51_00171(kmo)
SYN: sll1091
SYY: SYNGTS_1764(chlP)
SYT: SYNGTI_1764(chlP)
SYS: SYNPCCN_1763(chlP)
SYQ: SYNPCCP_1763(chlP)
SYJ: D082_12250(chlP)
SYO: C7I86_09185(chlP)
SYC: syc1129_d(chlP)
SYW: SYNW1097(chlP)
SYG: sync_1282(chlP)
SYR: SynRCC307_1267(chlP)
SYX: SynWH7803_1317(chlP)
SYP: SYNPCC7002_A2476(chlP)
CYA: CYA_0072(chlP)
CYB: CYB_1761(chlP)
SYNR: KR49_02790
SYND: KR52_10480
SYH: Syncc8109_1450(chlP)
SYNW: SynWH8103_01240(chlP)
SYNC: CB0101_03220(chlP)
TEL: tll0150(chlP)
THN: NK55_09970(chlP)
TVN: NIES2134_123820(chlP)
THEC: FFX45_11910(chlP)
CYI: CBM981_0621(chlP)
HHG: XM38_015980(chlP_2)
PSER: ABRG53_0355(chlP)
PMA: Pro_0832(chlP)
PMM: PMM0760(chlP)
PMT: PMT_0577
PMB: A9601_08221(chlP)
PMC: P9515_08231(chlP)
PMF: P9303_16731(chlP)
PMG: P9301_08201(chlP)
PMH: P9215_08541(chlP)
PMJ: P9211_10031(chlP)
PME: NATL1_07961(chlP)
PRC: EW14_0849
PRM: EW15_0845
AMR: AM1_2046(chlP)
THEU: HPC62_18410(chlP)
CHON: NIES4102_17970(chlP)
MAR: MAE_50020(chlP)
MPK: VL20_2943
MVZ: myaer102_23260(chlP)
CYL: AA637_11455(chlP)
ENN: FRE64_09415(chlP)
CYT: cce_3146(chlP)
TER: Tery_1823
ARP: NIES39_E00570(chlP)
PAGH: NIES204_40830(chlP)
OXY: HCG48_23715(chlP)
LFS: HFV01_21020(chlP)
GVI: gvip568(chlP)
GLJ: GKIL_3454(chlP)
ANA: alr0128(chlP)
NOE: CLI64_23700(chlP)
NSH: GXM_02661
AVA: Ava_1497
NAZ: Aazo_4038
ANB: ANA_C12069(chlP)
ANN: EH233_05305(chlP)
CALH: IJ00_23305
DOU: BMF77_03658(kmo)
TOQ: HCG51_14735(chlP)
CTHE: Chro_3960
STAN: STA3757_13410(chlP)
RCA: Rcas_3751
CAU: Caur_2087
CAG: Cagg_2633
CTE: CT2256(bchP)
CPC: Cpar_0021
CCH: Cag_0035
CLI: Clim_0022
PVI: Cvib_0020
PLT: Plut_0016
PPH: Ppha_0029
PAA: Paes_0023
PROC: Ptc2401_00022(cbrA)
CTS: Ctha_1271
 » show all
Reference
1  [PMID:7947681]
  Authors
Bollivar DW, Wang S, Allen JP, Bauer CE
  Title
Molecular genetic analysis of terminal steps in bacteriochlorophyll a biosynthesis: characterization of a Rhodobacter capsulatus strain that synthesizes geranylgeraniol-esterified bacteriochlorophyll a.
  Journal
Biochemistry 33:12763-8 (1994)
DOI:10.1021/bi00209a006
  Sequence
Reference
2  [PMID:10572128]
  Authors
Addlesee HA, Hunter CN
  Title
Physical mapping and functional assignment of the geranylgeranyl-bacteriochlorophyll reductase gene, bchP, of Rhodobacter sphaeroides.
  Journal
J Bacteriol 181:7248-55 (1999)
DOI:10.1128/JB.181.23.7248-7255.1999
  Sequence
Reference
3  [PMID:11872709]
  Authors
Addlesee HA, Hunter CN
  Title
Rhodospirillum rubrum possesses a variant of the bchP gene, encoding geranylgeranyl-bacteriopheophytin reductase.
  Journal
J Bacteriol 184:1578-86 (2002)
DOI:10.1128/JB.184.6.1578-1586.2002
  Sequence
[rru:Rru_A0629]
Reference
4  [PMID:18846281]
  Authors
Harada J, Miyago S, Mizoguchi T, Azai C, Inoue K, Tamiaki H, Oh-oka H
  Title
Accumulation of chlorophyllous pigments esterified with the geranylgeranyl group  and photosynthetic competence in the CT2256-deleted mutant of the green sulfur bacterium Chlorobium tepidum.
  Journal
Photochem Photobiol Sci 7:1179-87 (2008)
DOI:10.1039/b802435a
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.111
IUBMB Enzyme Nomenclature: 1.3.1.111
ExPASy - ENZYME nomenclature database: 1.3.1.111
BRENDA, the Enzyme Database: 1.3.1.111
LinkDB

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