KEGG   ENZYME: 1.3.1.19
Entry
EC 1.3.1.19                 Enzyme                                 
Name
cis-1,2-dihydrobenzene-1,2-diol dehydrogenase;
cis-benzene glycol dehydrogenase;
cis-1,2-dihydrocyclohexa-3,5-diene (nicotinamide adenine dinucleotide) oxidoreductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
cis-1,2-dihydrobenzene-1,2-diol:NAD+ oxidoreductase
Reaction(IUBMB)
cis-1,2-dihydrobenzene-1,2-diol + NAD+ = catechol + NADH + H+ [RN:R00812]
Reaction(KEGG)
R00812;
(other) R04088 R05354 R07703
Substrate
cis-1,2-dihydrobenzene-1,2-diol [CPD:C04091];
NAD+ [CPD:C00003]
Product
catechol [CPD:C00090];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.3.1.19 created 1972
Pathway
ec00361  Chlorocyclohexane and chlorobenzene degradation
ec00362  Benzoate degradation
ec00623  Toluene degradation
ec00624  Polycyclic aromatic hydrocarbon degradation
ec00643  Styrene degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K16269  cis-1,2-dihydrobenzene-1,2-diol/chlorobenzene dihydrodiol dehydrogenase
Genes
PPFPput_2877
PPXT1E_4270(tobD)
PMONX969_10950
PMOTX970_10605
BPTBpet3742(hcaB)
Reference
1  [PMID:4362337]
  Authors
Axcell BC, Geary PJ.
  Title
The metabolism of benzene by bacteria. Purification and some properties of the enzyme cis-1,2-dihydroxycyclohexa-3,5-diene (nicotinamide adenine dinucleotide) oxidoreductase (cis-benzene glycol dehydrogenase).
  Journal
Biochem J 136:927-34 (1973)
DOI:10.1042/bj1360927
Reference
2  [PMID:4298226]
  Authors
Gibson DT, Koch JR, Kallio RE.
  Title
Oxidative degradation of aromatic hydrocarbons by microorganisms. I. Enzymatic formation of catechol from benzene.
  Journal
Biochemistry 7:2653-62 (1968)
DOI:10.1021/bi00847a031
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.19
IUBMB Enzyme Nomenclature: 1.3.1.19
ExPASy - ENZYME nomenclature database: 1.3.1.19
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.19
BRENDA, the Enzyme Database: 1.3.1.19
CAS: 51923-03-6
LinkDB

DBGET integrated database retrieval system