| Entry |
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| Name |
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase;
3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase;
3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase;
dihydrodihydroxybenzoate dehydrogenase;
DHBDH;
cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase;
2-hydro-1,2-dihydroxybenzoate dehydrogenase;
cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase;
dihydrodihydroxybenzoate dehydrogenase;
(1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)
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| Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)
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| Reaction(IUBMB) |
(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+ = catechol + CO2 + NADH + H+ [RN: R00813]
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| Reaction(KEGG) |
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| Substrate |
(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate [CPD: C06321];
NAD+ [CPD: C00003]
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| Product |
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| History |
EC 1.3.1.25 created 1976, modified 2004 (EC 1.3.1.55 created 1999, incorporated 2004)
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| Pathway |
| ec01120 | Microbial metabolism in diverse environments |
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| Orthology |
| K05783 | dihydroxycyclohexadiene carboxylate dehydrogenase |
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| Genes |
» show all
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| Reference |
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| Authors |
Reiner AM. |
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| Title |
Metabolism of aromatic compounds in bacteria. Purification and properties of the catechol-forming enzyme, 3,5-cyclohexadiene-1,2-diol-1-carboxylic acid (NAD + ) oxidoreductase (decarboxylating). |
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| Journal |
J Biol Chem 247:4960-5 (1972) |
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| Reference |
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| Authors |
Neidle E, Hartnett C, Ornston LN, Bairoch A, Rekik M, Harayama S |
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| Title |
cis-diol dehydrogenases encoded by the TOL pWW0 plasmid xylL gene and the Acinetobacter calcoaceticus chromosomal benD gene are members of the short-chain alcohol dehydrogenase superfamily. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.3.1.25 |
| ExPASy - ENZYME nomenclature database: | 1.3.1.25 |
| UM-BBD (Biocatalysis/Biodegradation Database): | 1.3.1.25 |
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| LinkDB |
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