| Entry |
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| Name |
geranylgeranyl diphosphate reductase;
geranylgeranyl reductase;
CHL P
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| Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
geranylgeranyl-diphosphate:NADP+ oxidoreductase
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| Reaction(IUBMB) |
phytyl diphosphate + 3 NADP+ = geranylgeranyl diphosphate + 3 NADPH + 3 H+ [RN: R02063]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
This enzyme also acts on geranylgeranyl-chlorophyll a. The reaction occurs in three steps. Which order the three double bonds are reduced is not known.
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| History |
EC 1.3.1.83 created 2009
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| Pathway |
| ec00900 | Terpenoid backbone biosynthesis |
| ec01110 | Biosynthesis of secondary metabolites |
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| Orthology |
| K10960 | geranylgeranyl diphosphate/geranylgeranyl-bacteriochlorophyllide a reductase |
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| Genes |
» show all
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| Reference |
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| Authors |
Soll J, Schultz G, Rudiger W, Benz J |
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| Title |
Hydrogenation of Geranylgeraniol : Two Pathways Exist in Spinach Chloroplasts. |
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| Journal |
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| Reference |
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| Authors |
Tanaka R, Oster U, Kruse E, Rudiger W, Grimm B |
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| Title |
Reduced activity of geranylgeranyl reductase leads to loss of chlorophyll and tocopherol and to partially geranylgeranylated chlorophyll in transgenic tobacco plants expressing antisense RNA for geranylgeranyl reductase |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Keller Y, Bouvier F, d'Harlingue A, Camara B |
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| Title |
Metabolic compartmentation of plastid prenyllipid biosynthesis--evidence for the involvement of a multifunctional geranylgeranyl reductase. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.3.1.83 |
| ExPASy - ENZYME nomenclature database: | 1.3.1.83 |
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| LinkDB |
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