KEGG   ENZYME: 1.3.8.10
Entry
EC 1.3.8.10                 Enzyme                                 

Name
cyclohex-1-ene-1-carbonyl-CoA dehydrogenase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With a flavin as acceptor
Sysname
cyclohex-1-ene-1-carbonyl-CoA:electron transfer flavoprotein oxidoreductase
Reaction(IUBMB)
cyclohex-1-ene-1-carbonyl-CoA + electron-transfer flavoprotein = cyclohex-1,5-diene-1-carbonyl-CoA + reduced electron-transfer flavoprotein [RN:R09252]
Reaction(KEGG)
R09252
Substrate
cyclohex-1-ene-1-carbonyl-CoA [CPD:C09811];
electron-transfer flavoprotein [CPD:C04253]
Product
cyclohex-1,5-diene-1-carbonyl-CoA [CPD:C06322];
reduced electron-transfer flavoprotein [CPD:C04570]
Comment
Contains FAD. The enzyme, characterized from the strict anaerobic bacterium Syntrophus aciditrophicus, is involved in production of cyclohexane-1-carboxylate, a byproduct produced by that organism during fermentation of benzoate and crotonate to acetate.
History
EC 1.3.8.10 created 2013
Pathway
ec00362  Benzoate degradation
ec01120  Microbial metabolism in diverse environments
Orthology
K19066  cyclohex-1-ene-1-carbonyl-CoA dehydrogenase
Genes
GME: Gmet_3306
GBM: Gbem_3575
GEO: Geob_2191
SAT: SYN_02587
Reference
1  [PMID:23667239]
  Authors
Kung JW, Seifert J, von Bergen M, Boll M
  Title
Cyclohexanecarboxyl-coenzyme A (CoA) and cyclohex-1-ene-1-carboxyl-CoA dehydrogenases, two enzymes involved in the fermentation of benzoate and crotonate in Syntrophus aciditrophicus.
  Journal
J Bacteriol 195:3193-200 (2013)
DOI:10.1128/JB.00322-13
  Sequence
[sat:SYN_02587]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.8.10
IUBMB Enzyme Nomenclature: 1.3.8.10
ExPASy - ENZYME nomenclature database: 1.3.8.10
BRENDA, the Enzyme Database: 1.3.8.10
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