Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor

glycine:oxygen oxidoreductase (deaminating)

glycine + H2O + O2 = glyoxylate + NH3 + H2O2 (overall reaction) [RN:R00366];
(1a) glycine + O2 = 2-iminoacetate + H2O2 [RN:R07463];
(1b) 2-iminoacetate + H2O = glyoxylate + NH3 [RN:R10245]

R00366 R07463 R10245;
(other) R05861 R05862 R05863

glycine [CPD:C00037];
H2O [CPD:C00001];
O2 [CPD:C00007];
2-iminoacetate [CPD:C15809]

A flavoenzyme containing non-covalently bound FAD. The enzyme from Bacillus subtilis is active with glycine, sarcosine, N-ethylglycine, D-alanine, D-alpha-aminobutyrate, D-proline, D-pipecolate and N-methyl-D-alanine. It differs from EC 1.4.3.3, D-amino-acid oxidase, due to its activity on sarcosine and D-pipecolate. The intermediate 2-iminoacetate is used directly by EC 2.8.1.10, thiazole synthase.

EC 1.4.3.19 created 2002, modified 2012