Entry |
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Name |
salicylate 1-O-methyltransferase;
SAMT;
S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase;
salicylate carboxymethyltransferase
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Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
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Sysname |
S-adenosyl-L-methionine:salicylate 1-O-methyltransferase
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Reaction(IUBMB) |
S-adenosyl-L-methionine + salicylate = S-adenosyl-L-homocysteine + methyl salicylate [RN: R10448]
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Reaction(KEGG) |
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Substrate |
S-adenosyl-L-methionine [CPD: C00019];
salicylate [CPD: C00805]
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Product |
S-adenosyl-L-homocysteine [CPD: C00021];
methyl salicylate [CPD: C12305]
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Comment |
The enzyme, which is found in flowering plants, also has the activity of EC 2.1.1.273, benzoate O-methyltransferase.
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History |
EC 2.1.1.274 created 2013
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Orthology |
K21483 | salicylate 1-O-methyltransferase |
K21484 | benzoate/salicylate 1-O-methyltransferase |
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Genes |
» show all
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Reference |
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Authors |
Ross JR, Nam KH, D'Auria JC, Pichersky E |
Title |
S-Adenosyl-L-methionine:salicylic acid carboxyl methyltransferase, an enzyme involved in floral scent production and plant defense, represents a new class of plant methyltransferases. |
Journal |
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Sequence |
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Reference |
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Authors |
Negre F, Kolosova N, Knoll J, Kish CM, Dudareva N |
Title |
Novel S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase, an enzyme responsible for biosynthesis of methyl salicylate and methyl benzoate, is not involved in floral scent production in snapdragon flowers. |
Journal |
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Reference |
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Authors |
Chen F, D'Auria JC, Tholl D, Ross JR, Gershenzon J, Noel JP, Pichersky E |
Title |
An Arabidopsis thaliana gene for methylsalicylate biosynthesis, identified by a biochemical genomics approach, has a role in defense. |
Journal |
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Sequence |
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Reference |
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Authors |
Zubieta C, Ross JR, Koscheski P, Yang Y, Pichersky E, Noel JP |
Title |
Structural basis for substrate recognition in the salicylic acid carboxyl methyltransferase family. |
Journal |
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Sequence |
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Other DBs |
ExPASy - ENZYME nomenclature database: | 2.1.1.274 |
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LinkDB |
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