Entry |
|
Name |
protein-glutamate O-methyltransferase;
methyl-accepting chemotaxis protein O-methyltransferase;
S-adenosylmethionine-glutamyl methyltransferase;
methyl-accepting chemotaxis protein methyltransferase II;
S-adenosylmethionine:protein-carboxyl O-methyltransferase;
protein methylase II;
MCP methyltransferase I;
MCP methyltransferase II;
protein O-methyltransferase;
protein(aspartate)methyltransferase;
protein(carboxyl)methyltransferase;
protein carboxyl-methylase;
protein carboxyl-O-methyltransferase;
protein carboxylmethyltransferase II;
protein carboxymethylase;
protein carboxymethyltransferase;
protein methyltransferase II
|
Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
|
Sysname |
S-adenosyl-L-methionine:protein-L-glutamate O-methyltransferase
|
Reaction(IUBMB) |
S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate methyl ester [RN: R02623]
|
Reaction(KEGG) |
|
Substrate |
S-adenosyl-L-methionine [CPD: C00019];
protein L-glutamate [CPD: C00614]
|
Product |
S-adenosyl-L-homocysteine [CPD: C00021];
protein L-glutamate methyl ester [CPD: C04142]
|
Comment |
Forms ester groups with L-glutamate residues in a number of membrane proteins.
|
History |
EC 2.1.1.80 created 1989 (EC 2.1.1.24 created 1972, modified 1983, modified 1989, part incorporated 1992)
|
Orthology |
K00575 | chemotaxis protein methyltransferase CheR |
K13924 | two-component system, chemotaxis family, CheB/CheR fusion protein |
|
Genes |
» show all
|
Reference |
|
Authors |
Burgess-Cassler A, Ullah AH, Ordal GW. |
Title |
Purification and characterization of Bacillus subtilis methyl-accepting chemotaxis protein methyltransferase II. |
Journal |
J Biol Chem 257:8412-7 (1982) |
Reference |
|
Authors |
Kleene SJ, Toews ML, Adler J. |
Title |
Isolation of glutamic acid methyl ester from an Escherichia coli membrane protein involved in chemotaxis. |
Journal |
J Biol Chem 252:3214-8 (1977) |
Reference |
|
Authors |
Simms SA, Stock AM, Stock JB |
Title |
Purification and characterization of the S-adenosylmethionine:glutamyl methyltransferase that modifies membrane chemoreceptor proteins in bacteria. |
Journal |
J Biol Chem 262:8537-43 (1987) |
Sequence |
|
Reference |
|
Authors |
Springer WR, Koshland DE Jr. |
Title |
Identification of a protein methyltransferase as the cheR gene product in the bacterial sensing system. |
Journal |
|
Other DBs |
ExplorEnz - The Enzyme Database: | 2.1.1.80 |
ExPASy - ENZYME nomenclature database: | 2.1.1.80 |
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LinkDB |
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