KEGG   ENZYME: 2.1.3.6Help
Entry
EC 2.1.3.6                  Enzyme                                 

Name
putrescine carbamoyltransferase;
PTCase;
putrescine synthase;
putrescine transcarbamylase
Class
Transferases;
Transferring one-carbon groups;
Carboxy- and carbamoyltransferases
BRITE hierarchy
Sysname
carbamoyl-phosphate:putrescine carbamoyltransferase
Reaction(IUBMB)
carbamoyl phosphate + putrescine = phosphate + N-carbamoylputrescine [RN:R01399]
Reaction(KEGG)
Substrate
carbamoyl phosphate [CPD:C00169];
putrescine [CPD:C00134]
Product
phosphate [CPD:C00009];
N-carbamoylputrescine [CPD:C00436]
Comment
The plant enzyme also catalyses the reactions of EC 2.1.3.3 ornithine carbamoyltransferase, EC 2.7.2.2 carbamate kinase and EC 3.5.3.12 agmatine deiminase, thus acting as putrescine synthase, converting agmatine [(4-aminobutyl)guanidine] and ornithine into putrescine and citrulline, respectively.
History
EC 2.1.3.6 created 1976
Orthology
K13252  putrescine carbamoyltransferase
Genes
VHR: AL538_19730(argF)
VGA: BSQ33_19090
PPR: PBPRB1921(WS1753)
PGB: H744_1c0258
PLA: Plav_1142
HMC: HYPMC_3083(ptcA)
CAK: Caul_2960
HBC: AEM38_01040
STER: AOA14_07435
LMO: lmo0036
LMF: LMOf2365_0045(argF-1)
LMOG: BN389_00460(ptcA)
LMS: LMLG_0131
LMP: MUO_00230
LMW: LMOSLCC2755_0041(argF-1)
LMX: LMOSLCC2372_0036(argF-1)
LMZ: LMOSLCC2482_0041(argF-1)
LMOC: LMOSLCC5850_0036(argF-1)
LMOS: LMOSLCC7179_0042(argF-1)
LMOO: LMOSLCC2378_0045(argF-1)
LMOY: LMOSLCC2479_0036(argF-1)
LMOT: LMOSLCC2540_0042(argF-1)
LMOA: LMOATCC19117_0044(argF-1)
LMOL: LMOL312_0044(argF-1)
LMOE: BN418_0038
LMOB: BN419_0039
LMOD: LMON_0037
LMOW: AX10_08655
LMOX: AX24_12720
LMOQ: LM6179_0315(ptcA)
LMR: LMR479A_0043(ptcA)
LMOK: CQ02_00235
LMOM: IJ09_10195
LIV: LIV_0034
LLA: L0113(otcA)
LLK: LLKF_1862(pctA)
LLT: CVCAS_1609(pctA)
LLS: lilo_1676(otcA)
LLX: NCDO2118_1801(ptcA2)
LLW: kw2_1669(pctA)
LLJ: LG36_1655(pctA)
LPK: LACPI_2113(AguB)
SMU: SMU_262(otcA)
SMJ: SMULJ23_1707(otcA)
SMUA: SMUFR_0221(ptcA)
SCP: HMPREF0833_10548(argF)
LSA: LCA_0067
LBR: LVIS_2210
LBH: Lbuc_0314
LBN: LBUCD034_0348(pctA)
PPE: PEPE_0189
PPEN: T256_01065
PCE: PECL_1708(aguB)
EFA: EF0732(argF-2)
EFL: EF62_1118(agcB)
EFI: OG1RF_10469(argF)
EFS: EFS1_0578(otcA)
EFN: DENG_00782(ptcA)
EFQ: DR75_2688(argF)
ENE: ENT_23710
EFM: M7W_2228
EHR: EHR_01665
MMY: MSC_0703(arcB)
MMYM: MMS_A0772(argF)
MMYI: mycmycITA_00744(pyrB)
MML: MLC_6550(arcB)
MCP: MCAP_0654(argF)
MCAP: MCCPF38_00767(ptcA_2)
MCAR: MCCPILRI181_00770(ptcA_3)
MCAI: MCCG_0755
MLC: MSB_A0669(argF)
MLH: MLEA_006300(ptcA)
SERI: SERIO_v1c11430(ptcA)
EYY: EGYY_08400(ArgF) EGYY_08440(ArgF) EGYY_08490(ArgF) EGYY_17800(ArgF)
GPA: GPA_08150
AEQ: AEQU_1881
OLS: Olsu_1744
 » show all
Taxonomy
Reference
1  [PMID:4621632]
  Authors
Roon RJ, Barker HA.
  Title
Fermentation of agmatine in Streptococcus faecalis: occurrence of putrescine transcarbamoylase.
  Journal
J Bacteriol 109:44-50 (1972)
  Sequence
[efa:EF0732]
Reference
2  [PMID:6895223]
  Authors
Srivenugopal KS, Adiga PR.
  Title
Enzymic conversion of agmatine to putrescine in Lathyrus sativus seedlings. Purification and properties of a multifunctional enzyme (putrescine synthase).
  Journal
J Biol Chem 256:9532-41 (1981)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.3.6
IUBMB Enzyme Nomenclature: 2.1.3.6
ExPASy - ENZYME nomenclature database: 2.1.3.6
BRENDA, the Enzyme Database: 2.1.3.6
CAS: 9076-55-5
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