KEGG   ENZYME: 2.2.1.3
Entry
EC 2.2.1.3                  Enzyme                                 
Name
formaldehyde transketolase;
dihydroxyacetone synthase
Class
Transferases;
Transferring aldehyde or ketonic groups;
Transketolases and transaldolases
Sysname
D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase
Reaction(IUBMB)
D-xylulose 5-phosphate + formaldehyde = D-glyceraldehyde 3-phosphate + glycerone [RN:R01440]
Reaction(KEGG)
R01440;
(other) R06861 R06862
Substrate
D-xylulose 5-phosphate [CPD:C00231];
formaldehyde [CPD:C00067]
Product
D-glyceraldehyde 3-phosphate [CPD:C00118];
glycerone [CPD:C00184]
Comment
A thiamine-diphosphate protein. Not identical with EC 2.2.1.1 transketolase. Also converts hydroxypyruvate and formaldehyde into glycerone and CO2.
History
EC 2.2.1.3 created 1984
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K17100  dihydroxyacetone synthase
Genes
PPAPAS_chr3_0832 PAS_chr3_0834
DHADEHA2B00616g DEHA2F00968g
PICPICST_53327(DHA1)
PGUPGUG_01217
CTEN18249505(PSN45_000421)
SLBAWJ20_4479(TKL1)
OPAHPODL_02162 HPODL_04602
MGRMGG_09856
PPEIPpBr36_04039
PGRIPgNI_12421
TMNUCRPA7_3396 UCRPA7_4269
FGRFGSG_04065
FPUFPSE_05207
FPOAFPOAC1_006504
FVNFVRRES_07111
FVRFVEG_09977 FVEG_10248
FOXFOXG_11576 FOXG_11937
NHENECHADRAFT_49818 NECHADRAFT_81279 NECHADRAFT_85417 NECHADRAFT_94736
FFCNCS54_00784900 NCS54_01217300 NCS54_01246900 NCS54_01294400
FKRNCS57_00827300 NCS57_01204600
FMUJ7337_011514
TRETRIREDRAFT_2211
TRRM419DRAFT_131902
PCHMVFPPC_05404
AMUSLMH87_001124
PLJ28885255(PLICBS_006825) 90643476(PLICBS_009837)
PTKZJDV02_004704 JDV02_005468
VALVDBG_01162
VDAVDAG_00766
CFJCFIO01_03804
CLUPCLUP02_18273
CHIGCH63R_06688 CH63R_13541
SAPOSAPIO_CDS4846 SAPIO_CDS9476
ELAUCREL1_10531 UCREL1_1117
PFYPFICI_04079 PFICI_09160 PFICI_10610
BFUBCIN_03g03550
PSCOLY89DRAFT_706556
GLZGLAREA_06711
ANIANIA_08551 ANIA_08935
AFMAFUA_3G02910
NFINFIA_003880 NFIA_004690
AORAO090001000322 AO090023000345
ANGAn14g03500
AFVAFLA_006693 AFLA_008666
ALUCAKAW2_41032A AKAW2_80002A
ACHEACHE_70026A
APUUAPUU_30076S APUU_61016S APUU_80790S
PCSN7525_000016 N7525_000313 N7525_010047
TMFEYB26_008814
TRGTRUGW13939_01504 TRUGW13939_05090
PNOSNOG_09852
PTEPTT_19509
BZECOCCADRAFT_102944
BSCCOCSADRAFT_77503
BORCOCMIDRAFT_102603
AALTCC77DRAFT_1033210 CC77DRAFT_924107
ARABEKO05_0002641 EKO05_0011433
ZTRMYCGRDRAFT_86253
PFJMYCFIDRAFT_216533
FFUCLAFUR5_08012
CBETCB0940_04148
BCOMBAUCODRAFT_75705
NPAUCRNP2_5919
CNECNE00140 CNM01730
CNBCNBE0050 CNBM1610
CNGCNAG_02552 CNAG_06172
CGICGB_L0060W CGB_M2360C
CDEUCNBG_4484 CNBG_4878
TMSTREMEDRAFT_68833
CCACCcaHIS019_0705990(CcaverHIS019_0705990)
SHSSTEHIDRAFT_149842
MRRMoror_11317
SCMSCHCO_02629548(SCHCODRAFT_02629548)
PFPPFL1_02180
 » show all
Reference
1  [PMID:7249920]
  Authors
Bystrykh LV, Sokolov AP, Trotsenko IuA.
  Title
[Separation of transketolase and dihydroxyacetone synthase from methylotrophic yeasts]
  Journal
Dokl Akad Nauk SSSR 258:499-501 (1981)
Reference
2  [PMID:7074134]
  Authors
Kato N, Higuchi T, Sakazawa C, Nishizawa T, Tani Y, Yamada H
  Title
Purification and properties of a transketolase responsible for formaldehyde fixation in a methanol-utilizing yeast, candida boidinii (Kloeckera sp.) No. 2201.
  Journal
Biochim Biophys Acta 715:143-50 (1982)
DOI:10.1016/0304-4165(82)90352-X
Reference
3  [PMID:6276498]
  Authors
Waites MJ, Quayle JR.
  Title
The interrelation transketolase and dihydroxyacetone synthase activities in the methylotrophic yeast Candida boidinii.
  Journal
J Gen Microbiol 124:309-16 (1981)
DOI:10.1099/00221287-124-2-309
Other DBs
ExplorEnz - The Enzyme Database: 2.2.1.3
IUBMB Enzyme Nomenclature: 2.2.1.3
ExPASy - ENZYME nomenclature database: 2.2.1.3
BRENDA, the Enzyme Database: 2.2.1.3
CAS: 124566-23-0
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