KEGG   ENZYME: 2.3.1.137Help
Entry
EC 2.3.1.137                Enzyme                                 

Name
carnitine O-octanoyltransferase;
medium-chain/long-chain carnitine acyltransferase;
carnitine medium-chain acyltransferase;
easily solubilized mitochondrial carnitine palmitoyltransferase;
overt mitochondrial carnitine palmitoyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
octanoyl-CoA:L-carnitine O-octanoyltransferase
Reaction(IUBMB)
octanoyl-CoA + L-carnitine = CoA + L-octanoylcarnitine [RN:R03779]
Reaction(KEGG)
Substrate
octanoyl-CoA [CPD:C01944];
L-carnitine [CPD:C00318]
Product
CoA [CPD:C00010];
L-octanoylcarnitine [CPD:C02838]
Comment
Acts on a range of acyl-CoAs, with optimal activity with C6 or C8 acyl groups. cf. EC 2.3.1.7 (carnitine O-acetyltransferase) and EC 2.3.1.21 (carnitine O-palmitoyltransferase).
History
EC 2.3.1.137 created 1992
Orthology
K05940  carnitine O-octanoyltransferase
Genes
HSA: 54677(CROT)
PTR: 463514(CROT)
PPS: 100977046(CROT)
GGO: 101140286(CROT)
PON: 100452848(CROT)
NLE: 100601416(CROT)
MCC: 706186(CROT)
CSAB: 103226610(CROT)
RRO: 104668030(CROT)
RBB: 108515085(CROT)
CJC: 100399460(CROT)
SBQ: 101051126(CROT)
MMU: 74114(Crot)
RNO: 83842(Crot)
CGE: 100750995(Crot)
NGI: 103725174(Crot)
HGL: 101716437(Crot)
CCAN: 109695711(Crot)
OCU: 100355549(CROT)
TUP: 102478805(CROT)
CFA: 482283(CROT)
AML: 100475120(CROT)
UMR: 103658682(CROT)
ORO: 101367784(CROT)
FCA: 101096799(CROT)
PTG: 102972245(CROT)
AJU: 106987584(CROT)
BTA: 281092(CROT)
BOM: 102278173(CROT)
PHD: 102328865(CROT)
CHX: 102178596(CROT)
OAS: 101111626(CROT)
SSC: 100521142(CROT)
CFR: 102512006(CROT)
CDK: 105087356(CROT)
BACU: 103003725(CROT)
LVE: 103087959(CROT)
OOR: 101277059(CROT)
ECB: 100050111(CROT)
EPZ: 103541520(CROT)
EAI: 106844005(CROT)
MYB: 102246466(CROT)
MYD: 102755354(CROT)
HAI: 109371297(CROT)
RSS: 109457104(CROT)
PALE: 102880644(CROT)
LAV: 100673752(CROT)
TMU: 101348777
MDO: 100027224(CROT)
SHR: 100934458(CROT)
OAA: 100077745(CROT)
GGA: 420533(CROT)
MGP: 100548491(CROT)
CJO: 107309018(CROT)
APLA: 101793765(CROT)
ACYG: 106039688(CROT)
TGU: 100231530(CROT)
GFR: 102036972(CROT)
FAB: 101816162(CROT)
PHI: 102110439(CROT)
PMAJ: 107198602(CROT)
CCW: 104689198(CROT)
FPG: 101919746(CROT)
FCH: 102049905(CROT)
CLV: 102095452(CROT)
EGZ: 104128762(CROT)
AAM: 106483608(CROT)
ASN: 102386610(CROT)
AMJ: 102558111(CROT)
PSS: 102461470(CROT)
CMY: 102941072(CROT)
CPIC: 101942862(CROT)
ACS: 100564060(crot)
PVT: 110070292(CROT)
PBI: 103065388(CROT)
GJA: 107124960(CROT)
XLA: 108719881(crot.S)
XTR: 733879(crot)
NPR: 108795594(CROT)
DRE: 553204(crot)
IPU: 108256531(crot)
AMEX: 103046237(crot)
TRU: 101075450(crot)
MZE: 101470173
OLA: 101171357(crot)
XMA: 102224261(crot)
PRET: 103478127(crot)
NFU: 107379651(crot)
LCF: 108889589(crot)
HCQ: 109528977(acbd7)
ELS: 105018942(crot)
SFM: 108940735(crot)
LCM: 102358236(CROT)
CMK: 103181560(crot)
CIN: 100178156
SPU: 585404
APLC: 110985552
DME: Dmel_CG12428(CG12428)
DSI: Dsimw501_GD29096(Dsim_GD29096)
MDE: 101888731
AAG: 5566097
TUT: 107363886
CEL: CELE_F41E7.6(F41E7.6) CELE_T20B3.1(T20B3.1)
CBR: CBG23894
OBI: 106877705
EPA: 110239307
ADF: 107331942
HMG: 100205473
SPAR: SPRG_15834
 » show all
Taxonomy
Reference
1  [PMID:6436243]
  Authors
Farrell SO, Fiol CJ, Reddy JK, Bieber LL.
  Title
Properties of purified carnitine acyltransferases of mouse liver peroxisomes.
  Journal
J Biol Chem 259:13089-95 (1984)
  Sequence
[mmu:74114]
Reference
2  [PMID:3342008]
  Authors
Healy MJ, Kerner J, Bieber LL.
  Title
Enzymes of carnitine acylation. Is overt carnitine palmitoyltransferase of liver peroxisomal carnitine octanoyltransferase?
  Journal
Biochem J 249:231-7 (1988)
Reference
3  [PMID:6630173]
  Authors
Miyazawa S, Ozasa H, Osumi T, Hashimoto T.
  Title
Purification and properties of carnitine octanoyltransferase and carnitine palmitoyltransferase from rat liver.
  Journal
J Biochem (Tokyo) 94:529-42 (1983)
  Sequence
[rno:83842]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.137
IUBMB Enzyme Nomenclature: 2.3.1.137
ExPASy - ENZYME nomenclature database: 2.3.1.137
BRENDA, the Enzyme Database: 2.3.1.137
CAS: 39369-19-2
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