KEGG   ENZYME: 2.3.1.232
Entry
EC 2.3.1.232                Enzyme                                 

Name
methanol O-anthraniloyltransferase;
AMAT;
anthraniloyl-coenzyme A (CoA):methanol acyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
anthraniloyl-CoA:methanol O-anthraniloyltransferase
Reaction(IUBMB)
anthraniloyl-CoA + methanol = CoA + O-methyl anthranilate [RN:R10681]
Reaction(KEGG)
R10681
Substrate
anthraniloyl-CoA [CPD:C02247];
methanol [CPD:C00132]
Product
CoA [CPD:C00010];
O-methyl anthranilate [CPD:C20634]
Comment
The enzyme from Concord grape (Vitis labrusca) is solely responsible for the production of O-methyl anthranilate, an important aroma and flavor compound in the grape. The enzyme has a broad substrate specificity, and can use a range of alcohols with substantial activity, the best being butanol, benzyl alcohol, iso-pentanol, octanol and 2-propanol. It can use benzoyl-CoA and acetyl-CoA as acyl donors with lower efficiency. In addition to O-methyl anthranilate, the enzyme might be responsible for the production of ethyl butanoate, methyl-3-hydroxy butanoate and ethyl-3-hydroxy butanoate, which are present in large quantities in the grapes. Also catalyses EC 2.3.1.196, benzyl alcohol O-benzoyltransferase.
History
EC 2.3.1.232 created 2014
Orthology
K19861  benzyl alcohol O-benzoyltransferase
Genes
ATH: AT5G17540
CRB: 17882598 17883284
CSAT: 104706051 104706052 104735796 104735797 104770061 104770062
CIT: 102630782
CIC: CICLE_v10031489mg
EGR: 104427024
GMX: 100797017 100799685
GSJ: 114372437 114377355
PVU: PHAVU_007G280800g
VRA: 106769599
VAR: 108324959
VUN: 114191882
CCAJ: 109815603
CAM: 101508133
ADU: 107462813
AIP: 107613431
FVE: 101297794
RCN: 112173156
PMUM: 103331665
PAVI: 110755953
ZJU: 107432782
CSV: 101205621
CMO: 103501099(AAT3)
MCHA: 111017149
HBR: 110651562
MESC: 110622159
PEU: 105117135
JRE: 108996627
QSU: 112029458
CANN: 107877868
NTO: 104111677
NAU: 109212944
DCR: 108207978
BVG: 104889262
SOE: 110792434
NNU: 104610311
PSOM: 113297455
DOSA: Os01t0350000-01(Os01g0350000) Os05t0141300-00(Os05g0141300) Os06t0710700-01(Os06g0710700) Os07t0244200-01(Os07g0244200) Os07t0550600-01(Os07g0550600) Os10t0133500-01(Os10g0133500) Os10t0195600-01(Os10g0195600)
ATS: 109735002(LOC109735002) 109738690(LOC109738690) 109751661(LOC109751661) 109768200(LOC109768200)
PDA: 103699757
MUS: 103975095
ATR: 18422709
 » show all
Reference
1  [PMID:16262710]
  Authors
Wang J, De Luca V
  Title
The biosynthesis and regulation of biosynthesis of Concord grape fruit esters, including 'foxy' methylanthranilate.
  Journal
Plant J 44:606-19 (2005)
DOI:10.1111/j.1365-313X.2005.02552.x
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.232
IUBMB Enzyme Nomenclature: 2.3.1.232
ExPASy - ENZYME nomenclature database: 2.3.1.232
BRENDA, the Enzyme Database: 2.3.1.232
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