| Entry |
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| Name |
protein N-acetylglucosaminyltransferase;
uridine diphosphoacetylglucosamine-protein acetylglucosaminyltransferase;
uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase;
N-acetylglucosaminyltransferase I
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| Class |
Transferases;
Glycosyltransferases;
Hexosyltransferases
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| Sysname |
UDP-N-acetyl-D-glucosamine:[protein]-L-asparagine beta-N-acetyl-D-glucosaminyl-transferase
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| Reaction(IUBMB) |
UDP-N-acetyl-D-glucosamine + [protein]-L-asparagine = UDP + [protein]-N4-(N-acetyl-D-glucosaminyl)-L-asparagine [RN: R00417]
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| Reaction(KEGG) |
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| Substrate |
UDP-N-acetyl-D-glucosamine [CPD: C00043];
[protein]-L-asparagine
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| Product |
UDP [CPD: C00015];
[protein]-N4-(N-acetyl-D-glucosaminyl)-L-asparagine
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| Comment |
The acceptor is the asparagine residue in a sequence of the form Asn-Xaa-Thr or Asn-Xaa-Ser.
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| History |
EC 2.4.1.94 created 1978, modified 2010
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| Reference |
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| Authors |
Khalkhall Z, Marshall RD. |
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| Title |
Glycosylation of ribonuclease A catalysed by rabbit liver extracts. |
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| Journal |
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| Reference |
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| Authors |
Khalkhali Z, Marshall RD. |
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| Title |
UDP-N-acetyl-D-glucosamine-asparagine sequon N-acetyl-beta-D-glucosaminyl-transferase-activity in human serum. |
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| Journal |
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| Reference |
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| Authors |
Khalkhali Z, Marshall RD, Reuvers F, Habets-Willems C, Boer P. |
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| Title |
Glycosylation in vitro of an asparagine sequon catalysed by preparations of yeast cell membranes. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.4.1.94 |
| ExPASy - ENZYME nomenclature database: | 2.4.1.94 |
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| LinkDB |
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