| Entry |
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| Name |
fumigaclavine A dimethylallyltransferase;
FgaPT1
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| Class |
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
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| Sysname |
dimethylallyl-diphosphate:fumigaclavine A dimethylallyltransferase
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| Reaction(IUBMB) |
fumigaclavine A + dimethylallyl diphosphate = fumigaclavine C + diphosphate [RN: R10201]
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| Reaction(KEGG) |
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| Substrate |
fumigaclavine A [CPD: C20436];
dimethylallyl diphosphate [CPD: C00235]
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| Product |
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| Comment |
Fumigaclavine C is an ergot alkaloid produced by some fungi of the Trichocomaceae family. Activity does not require any metal ions.
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| History |
EC 2.5.1.100 created 2012
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| Pathway |
| ec00901 | Indole alkaloid biosynthesis |
| ec01110 | Biosynthesis of secondary metabolites |
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| Orthology |
| K14135 | fumigaclavine A dimethylallyltransferase |
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| Genes |
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| Reference |
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| Authors |
Unsold IA, Li SM |
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| Title |
Reverse prenyltransferase in the biosynthesis of fumigaclavine C in Aspergillus fumigatus: gene expression, purification, and characterization of fumigaclavine C synthase FGAPT1. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.5.1.100 |
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| LinkDB |
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