| Entry |
|
|---|
| Name |
7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase;
MJ0301 (gene name);
dihydropteroate synthase (ambiguous)
|
|---|
| Class |
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
|
|---|
| Sysname |
(7,8-dihydropterin-6-yl)methyl diphosphate:4-(beta-D-ribofuranosyl)aniline 5'-phosphate 6-hydroxymethyl-7,8-dihydropterintransferase
|
|---|
| Reaction(IUBMB) |
(7,8-dihydropterin-6-yl)methyl diphosphate + 4-(beta-D-ribofuranosyl)aniline 5'-phosphate = N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphate [RN: R10339]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
(7,8-dihydropterin-6-yl)methyl diphosphate [CPD: C04807];
4-(beta-D-ribofuranosyl)aniline 5'-phosphate [CPD: C20559]
|
|---|
| Product |
N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate [CPD: C20562];
diphosphate [CPD: C00013]
|
|---|
| Comment |
The enzyme, which has been studied in the archaeon Methanocaldococcus jannaschii, is involved in the biosynthesis of tetrahydromethanopterin.
|
|---|
| History |
EC 2.5.1.105 created 2013
|
|---|
| Pathway |
|
|---|
| Orthology |
| K06897 | 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase |
|
|---|
| Genes |
» show all
|
|---|
| Reference |
|
|---|
| Authors |
Xu H, Aurora R, Rose GD, White RH |
|---|
| Title |
Identifying two ancient enzymes in Archaea using predicted secondary structure alignment. |
|---|
| Journal |
|
|---|
| Sequence |
|
|---|
| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.5.1.105 |
|
|---|
| LinkDB |
|
|---|
