| Entry |
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| Name |
5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase;
PpzP;
dihydrophenazine-1-carboxylate dimethylallyltransferase;
5,10-dihydrophenazine 1-carboxylate dimethylallyltransferase
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| Class |
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
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| Sysname |
dimethylallyl diphosphate:5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase
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| Reaction(IUBMB) |
dimethylallyl diphosphate + 5,10-dihydrophenazine-1-carboxylate = diphosphate + 9-(dimethylallyl)-5,10-dihydrophenazine-1-carboxylate [RN: R10966]
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| Reaction(KEGG) |
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| Substrate |
dimethylallyl diphosphate [CPD: C00235];
5,10-dihydrophenazine-1-carboxylate [CPD: C20981]
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| Product |
diphosphate [CPD: C00013];
9-(dimethylallyl)-5,10-dihydrophenazine-1-carboxylate [CPD: C20982]
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| Comment |
The enzyme is involved in the biosynthesis of prenylated phenazines by the bacterium Streptomyces anulatus. It is specific for both dimethylallyl diphosphate and 5,10-dihydrophenazine-1-carboxylate.
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| History |
EC 2.5.1.121 created 2014
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| Pathway |
| ec01130 | Biosynthesis of antibiotics |
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| Orthology |
| K21338 | 5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase |
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| Reference |
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| Authors |
Saleh O, Gust B, Boll B, Fiedler HP, Heide L |
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| Title |
Aromatic prenylation in phenazine biosynthesis: dihydrophenazine-1-carboxylate dimethylallyltransferase from Streptomyces anulatus. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.5.1.121 |
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| LinkDB |
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