Entry |
|
Name |
4-O-dimethylallyl-L-tyrosine synthase;
SirD
|
Class |
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
|
Sysname |
dimethylallyl diphosphate:L-tyrosine 4-O-dimethylallyltransferase
|
Reaction(IUBMB) |
dimethylallyl diphosphate + L-tyrosine = diphosphate + 4-O-dimethylallyl-L-tyrosine [RN: R10968]
|
Reaction(KEGG) |
|
Substrate |
dimethylallyl diphosphate [CPD: C00235];
L-tyrosine [CPD: C00082]
|
Product |
diphosphate [CPD: C00013];
4-O-dimethylallyl-L-tyrosine [CPD: C20983]
|
Comment |
The enzyme is involved in biosynthesis of the phytotoxin sirodesmin PL by the phytopathogenic ascomycete Leptosphaeria maculans.
|
History |
EC 2.5.1.122 created 2014
|
Orthology |
K21339 | 4-O-dimethylallyl-L-tyrosine synthase |
|
Genes |
|
Reference |
|
Authors |
Kremer A, Li SM |
Title |
A tyrosine O-prenyltransferase catalyses the first pathway-specific step in the biosynthesis of sirodesmin PL. |
Journal |
|
Sequence |
|
Reference |
|
Authors |
Zou HX, Xie X, Zheng XD, Li SM |
Title |
The tyrosine O-prenyltransferase SirD catalyzes O-, N-, and C-prenylations. |
Journal |
|
Sequence |
|
Other DBs |
ExPASy - ENZYME nomenclature database: | 2.5.1.122 |
|
LinkDB |
|