| Entry |
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| Name |
4-O-dimethylallyl-L-tyrosine synthase;
SirD
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| Class |
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
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| Sysname |
dimethylallyl diphosphate:L-tyrosine 4-O-dimethylallyltransferase
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| Reaction(IUBMB) |
dimethylallyl diphosphate + L-tyrosine = diphosphate + 4-O-dimethylallyl-L-tyrosine [RN: R10968]
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| Reaction(KEGG) |
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| Substrate |
dimethylallyl diphosphate [CPD: C00235];
L-tyrosine [CPD: C00082]
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| Product |
diphosphate [CPD: C00013];
4-O-dimethylallyl-L-tyrosine [CPD: C20983]
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| Comment |
The enzyme is involved in biosynthesis of the phytotoxin sirodesmin PL by the phytopathogenic ascomycete Leptosphaeria maculans.
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| History |
EC 2.5.1.122 created 2014
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| Orthology |
| K21339 | 4-O-dimethylallyl-L-tyrosine synthase |
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| Genes |
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| Reference |
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| Authors |
Kremer A, Li SM |
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| Title |
A tyrosine O-prenyltransferase catalyses the first pathway-specific step in the biosynthesis of sirodesmin PL. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Zou HX, Xie X, Zheng XD, Li SM |
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| Title |
The tyrosine O-prenyltransferase SirD catalyzes O-, N-, and C-prenylations. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.5.1.122 |
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| LinkDB |
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