Entry |
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Name |
coumarin 8-geranyltransferase;
ClPT1
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Class |
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
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Sysname |
geranyl diphosphate:umbelliferone 8-geranyltransferase
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Reaction(IUBMB) |
(1) geranyl diphosphate + umbelliferone = diphosphate + 8-geranylumbelliferone [RN: R11602];
(2) geranyl diphosphate + esculetin = diphosphate + 8-geranylesculetin [RN: R11603]
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Reaction(KEGG) |
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Substrate |
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Product |
diphosphate [CPD: C00013];
8-geranylumbelliferone [CPD: C21495];
8-geranylesculetin [CPD: C21496]
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Comment |
The enzyme, characterized from the plant Citrus limon, is specific for geranyl diphosphate as a prenyl donor. It also has low activity with the coumarins 5,7-dihydroxycoumarin and 5-methoxy-7-hydroxycoumarin.
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History |
EC 2.5.1.138 created 2017
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Orthology |
K21587 | coumarin 8-geranyltransferase |
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Genes |
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Reference |
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Authors |
Munakata R, Inoue T, Koeduka T, Karamat F, Olry A, Sugiyama A, Takanashi K, Dugrand A, Froelicher Y, Tanaka R, Uto Y, Hori H, Azuma J, Hehn A, Bourgaud F, Yazaki K |
Title |
Molecular cloning and characterization of a geranyl diphosphate-specific aromatic prenyltransferase from lemon. |
Journal |
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Sequence |
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Other DBs |
ExPASy - ENZYME nomenclature database: | 2.5.1.138 |
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LinkDB |
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