| Entry |
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| Name |
thiamine pyridinylase;
pyrimidine transferase;
thiaminase I;
thiamin hydrolase;
thiamin pyridinolase;
thiaminase (ambiguous);
thiamine pyridinolase;
thiamin pyridinylase;
thiamin:base 2-methyl-4-aminopyrimidine-5-methenyltransferase
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| Class |
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
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| Sysname |
thiamine:base 2-methyl-4-aminopyrimidine-5-methenyltransferase
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| Reaction(IUBMB) |
thiamine + pyridine = 1-[(4-amino-2-methylpyrimidin-5-yl)methyl]pyridinium + 4-methyl-5-(2-hydroxyethyl)thiazole [RN: R02863]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
1-[(4-amino-2-methylpyrimidin-5-yl)methyl]pyridinium [CPD: C02691];
4-methyl-5-(2-hydroxyethyl)thiazole [CPD: C04294]
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| Comment |
Various bases and thiol compounds can act instead of pyridine.
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| History |
EC 2.5.1.2 created 1961, modified 1976, modified 2001
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| Pathway |
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| Orthology |
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| Genes |
» show all
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| Reference |
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| Authors |
FUJITA A. |
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| Title |
Thiaminase. |
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| Journal |
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| Reference |
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| Authors |
KENTEN RH. |
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| Title |
[Pteridium aquilinum (L.) Kuhn.] |
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| Journal |
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| Reference |
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| Authors |
Wittliff JL, Airth RL. |
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| Title |
The extracellular thiaminase I of Bacillus thiaminolyticus. I. Purification and physicochemical properties. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.5.1.2 |
| ExPASy - ENZYME nomenclature database: | 2.5.1.2 |
| BRENDA, the Enzyme Database: | 2.5.1.2 |
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| LinkDB |
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