KEGG   ENZYME: 2.6.1.116Help
Entry
EC 2.6.1.116                Enzyme                                 

Name
6-aminohexanoate aminotransferase;
nylD (gene name)
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
6-aminohexanoate:2-oxogutarate aminotransferase
Reaction(IUBMB)
6-aminohexanoate + 2-oxoglutarate = 6-oxohexanoate + L-glutamate [RN:R05507]
Reaction(KEGG)
Substrate
6-aminohexanoate [CPD:C02378];
2-oxoglutarate [CPD:C00026]
Product
6-oxohexanoate [CPD:C06102];
L-glutamate [CPD:C00025]
Comment
The enzyme, characterized from the bacterium Arthrobacter sp. KI72, participates in the degradation of nylon-6. Glyoxylate can serve as an alternative amino group acceptor with similar efficiency.
History
EC 2.6.1.116 created 2019
Pathway
ec00930  Caprolactam degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Reference
1  [PMID:29188330]
  Authors
Takehara I, Fujii T, Tanimoto Y, Kato DI, Takeo M, Negoro S
  Title
Metabolic pathway of 6-aminohexanoate in the nylon oligomer-degrading bacterium Arthrobacter sp. KI72: identification of the enzymes responsible for the conversion of 6-aminohexanoate to adipate.
  Journal
Appl Microbiol Biotechnol 102:801-814 (2018)
DOI:10.1007/s00253-017-8657-y
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.116
IUBMB Enzyme Nomenclature: 2.6.1.116
ExPASy - ENZYME nomenclature database: 2.6.1.116
BRENDA, the Enzyme Database: 2.6.1.116
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