KEGG   ENZYME: 2.7.1.229
Entry
EC 2.7.1.229                Enzyme                                 

Name
deoxyribokinase;
deoK (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
ATP:2-deoxy-D-ribose 5-phosphotransferase
Reaction(IUBMB)
ATP + 2-deoxy-D-ribose = ADP + 2-deoxy-D-ribose 5-phosphate [RN:R02750]
Reaction(KEGG)
R02750
Substrate
ATP [CPD:C00002];
2-deoxy-D-ribose [CPD:C01801]
Product
ADP [CPD:C00008];
2-deoxy-D-ribose 5-phosphate [CPD:C00673]
Comment
The enzyme, characterized from bacteria, is much more active with 2-deoxy-D-ribose than with D-ribose. cf. EC 2.7.1.15, ribokinase.
History
EC 2.7.1.229 created 2019
Reference
1  [PMID:13563487]
  Authors
DOMAGK GF, HORECKER BL
  Title
Pentose fermentation by Lactobacillus plantarum. V. Fermentation of 2-deoxy-D-ribose.
  Journal
J Biol Chem 233:283-6 (1958)
Reference
2  [PMID:13641245]
  Authors
GINSBURG A.
  Title
A deoxyribokinase from Lactobacillus plantarum.
  Journal
J Biol Chem 234:481-7 (1959)
Reference
3  [PMID:4867740]
  Authors
Hoffee PA
  Title
2-deoxyribose gene-enzyme complex in Salmonella typhimurium. I. Isolation and enzymatic characterization of 2-deoxyribose-negative mutants.
  Journal
J Bacteriol 95:449-57 (1968)
DOI:10.1128/JB.95.2.449-457.1968
Reference
4  [PMID:10648508]
  Authors
Tourneux L, Bucurenci N, Saveanu C, Kaminski PA, Bouzon M, Pistotnik E, Namane A, Marliere P, Barzu O, Li De La Sierra I, Neuhard J, Gilles AM
  Title
Genetic and biochemical characterization of Salmonella enterica serovar typhi deoxyribokinase.
  Journal
J Bacteriol 182:869-73 (2000)
DOI:10.1128/jb.182.4.869-873.2000
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.229
IUBMB Enzyme Nomenclature: 2.7.1.229
ExPASy - ENZYME nomenclature database: 2.7.1.229
BRENDA, the Enzyme Database: 2.7.1.229
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