EC 184.108.40.206 Enzyme
[acetyl-CoA carboxylase] kinase;
acetyl coenzyme A carboxylase kinase (phosphorylating);
acetyl-CoA carboxylase bound kinase;
acetyl-CoA carboxylase kinase;
acetyl-CoA carboxylase kinase (cAMP-independent);
acetyl-CoA carboxylase kinase 2;
acetyl-CoA carboxylase kinase-2;
acetyl-CoA carboxylase kinase-3 (AMP-activated);
acetyl-coenzyme A carboxylase kinase;
Transferring phosphorus-containing groups;
ATP:[acetyl-CoA carboxylase] phosphotransferase
ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate [RN:
[acetyl-CoA carboxylase] [CPD:
[acetyl-CoA carboxylase] phosphate [CPD:
Phosphorylates and inactivates EC
, acetyl-CoA carboxylase, which can be dephosphorylated and reactivated by EC
, [phosphorylase] phosphatase. The enzyme is more active towards the dimeric form of acetyl-CoA carboxylase than the polymeric form . Phosphorylates serine residues.
EC 220.127.116.11 created 1990 as EC 18.104.22.168 (EC 22.214.171.124 created 1984, incorporated 1992), transferred 2005 to EC 126.96.36.199
Jamil H, Madsen NB.
Phosphorylation state of acetyl-coenzyme A carboxylase. I. Linear inverse relationship to activity ratios at different citrate concentrations.
J Biol Chem 262:630-7 (1987)
Lent B, Kim KH.
Purification and properties of a kinase which phosphorylates and inactivates acetyl-CoA carboxylase.
J Biol Chem 257:1897-901 (1982)
Munday MR, Hardie DG.
Isolation of three cyclic-AMP-independent acetyl-CoA carboxylase kinases from lactating rat mammary gland and characterization of their effects on enzyme activity.
Eur J Biochem 141:617-27 (1984)
Mohamed AH, Huang WY, Huang W, Venkatachalam KV, Wakil SJ.
Isolation and characterization of a novel acetyl-CoA carboxylase kinase from rat liver.
J Biol Chem 269:6859-65 (1994)
Heesom KJ, Moule SK, Denton RM.
Purification and characterisation of an insulin-stimulated protein-serine kinase which phosphorylates acetyl-CoA carboxylase.
FEBS Lett 422:43-6 (1998)
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