EC 188.8.131.52 Enzyme
[tyrosine 3-monooxygenase] kinase;
pheochromocytoma tyrosine hydroxylase-associated kinase;
tyrosine 3-monooxygenase kinase (phosphorylating)
Transferring phosphorus-containing groups;
ATP + [tyrosine-3-monooxygenase] = ADP + phospho-[tyrosine-3-monooxygenase]
The enzyme has no activating compound but is specific for its substrate, with which it co-purifies. Requires Mg2+. Activates EC
, tyrosine 3-monooxygenase, by phosphorylation.
EC 184.108.40.206 created 1989 as EC 220.127.116.11, transferred 2005 to EC 18.104.22.168
Pigeon D, Drissi-Daoudi R, Gros F, Thibault J.
[Copurification of tyrosine hydroxylase from rat pheochromocytoma by protein kinase]
C R Acad Sci III 302:435-8 (1986)
Pigeon D, Ferrara P, Gros F, Thibault J.
Rat pheochromocytoma tyrosine hydroxylase is phosphorylated on serine 40 by an associated protein kinase.
J Biol Chem 262:6155-8 (1987)
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