Entry |
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Name |
nicotinamide-nucleotide adenylyltransferase;
NAD+ pyrophosphorylase;
adenosine triphosphate-nicotinamide mononucleotide transadenylase;
ATP:NMN adenylyltransferase;
diphosphopyridine nucleotide pyrophosphorylase;
nicotinamide adenine dinucleotide pyrophosphorylase;
nicotinamide mononucleotide adenylyltransferase;
NMN adenylyltransferase
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Class |
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
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Sysname |
ATP:nicotinamide-nucleotide adenylyltransferase
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Reaction(IUBMB) |
ATP + nicotinamide ribonucleotide = diphosphate + NAD+ [RN: R00137]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
Nicotinate nucleotide can also act as acceptor. See also EC 2.7.7.18 nicotinate-nucleotide adenylyltransferase.
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History |
EC 2.7.7.1 created 1961
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Pathway |
ec00760 | Nicotinate and nicotinamide metabolism |
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Orthology |
K00952 | nicotinamide-nucleotide adenylyltransferase |
K06210 | nicotinamide mononucleotide adenylyltransferase |
K06211 | HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes |
K13522 | bifunctional NMN adenylyltransferase/nudix hydrolase |
K19785 | nicotinamide-nucleotide adenylyltransferase |
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Genes |
» show all
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Reference |
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Authors |
ATKINSON MR, JACKSON JF, MORTON RK. |
Title |
Nicotinamide mononucleotide adenylyltransferase of pig-liver nuclei. The effects of nicotinamide mononucleotide concentration and pH on dinucleotide synthesis. |
Journal |
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Reference |
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Authors |
Dahmen W, Webb B, Preiss J. |
Title |
The deamido-diphosphopyridine nucleotide and diphosphopyridine nucleotide pyrophosphorylases of Escherichia coli and yeast. |
Journal |
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Reference |
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Authors |
KORNBERG A, PRICER WE Jr. |
Title |
Enzymatic cleavage of diphosphopyridine nucleotide with radioactive pyrophosphate. |
Journal |
J Biol Chem 191:535-41 (1951) |
Other DBs |
ExplorEnz - The Enzyme Database: | 2.7.7.1 |
ExPASy - ENZYME nomenclature database: | 2.7.7.1 |
BRENDA, the Enzyme Database: | 2.7.7.1 |
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LinkDB |
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