KEGG   ENZYME: 2.7.7.47
Entry
EC 2.7.7.47                 Enzyme                                 

Name
streptomycin 3''-adenylyltransferase;
streptomycin adenylate synthetase;
streptomycin adenyltransferase;
streptomycin adenylylase;
streptomycin adenylyltransferase;
streptomycin-spectinomycin adenylyltransferase;
AAD (3'');
aminoglycoside 3''-adenylyltransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
Sysname
ATP:streptomycin 3''-adenylyltransferase
Reaction(IUBMB)
ATP + streptomycin = diphosphate + 3''-adenylylstreptomycin [RN:R02226]
Reaction(KEGG)
R02226
Substrate
ATP [CPD:C00002];
streptomycin [CPD:C00413]
Product
diphosphate [CPD:C00013];
3''-adenylylstreptomycin [CPD:C03462]
Comment
Also acts on spectinomycin.
History
EC 2.7.7.47 created 1976
Orthology
K00984  streptomycin 3"-adenylyltransferase
Genes
CSAB: 103247768
NSY: 104236379
EUN: pUMNK88_130(aadA) pUMNK88_133(aadA2)
ECOS: EC958_A0109(aadA5)
ECV: APECO1_O1R89(aadA)
ECM: EcSMS35_A0135(aadA)
EUM: ECUMN_4816(aadA)
ELO: EC042_4093(aadA1)
ELN: NRG857_30102
STY: STY1857(aadA)
STT: t1142(aadA)
SEX: STBHUCCB_12250
SENT: TY21A_05790
STM: STM1264(aadA)
SEO: STM14_1525(aadA)
SEV: STMMW_12701
SEY: SL1344_1199(aadA)
SEM: STMDT12_C12800 STMDT12_C39240 STMDT12_L00640
SEJ: STMUK_1231(aadA)
SEB: STM474_1265(aadA)
SEF: UMN798_1312(aadA)
SETU: STU288_02640 STU288_1p00740 STU288_1p00750
SETC: CFSAN001921_10840
SENR: STMDT2_11961(aadA)
SEND: DT104_12401(aadA) DT104_38561
SENI: CY43_06435 CY43_20060
SEEN: SE451236_12180
SPT: SPA1582(aadA)
SEK: SSPA1470
SPQ: SPAB_02095
SEI: SPC_2479(aadA)
SEC: SCH_032(aadA2) SCH_051(aadA2) SCH_053(aadA2) SCH_1275(aadA)
SEH: SeHA_C1385
SHB: SU5_01885
SENH: CFSAN002069_02690 CFSAN002069_23195
SEEH: SEEH1578_00460 SEEH1578_15545
SEE: SNSL254_A1370 SNSL254_p_0144(aadA)
SENN: SN31241_23340 SN31241_6930
SEW: SeSA_A1354 SeSA_B0063 SeSA_B0065(aadA)
SEA: SeAg_B1916
SENS: Q786_08935
SEG: SG1860(aadA)
SEL: SPUL_1067(aadA)
SEGA: SPUCDC_1067(aadA)
SET: SEN1788(aadA)
SENA: AU38_09260
SENO: AU37_09265
SENV: AU39_09270
SENQ: AU40_10340
SENL: IY59_09475
SENJ: CFSAN001992_05275
SEEC: CFSAN002050_12715
SEEB: SEEB0189_013255
SEEP: I137_04900
SENB: BN855_12930
SENE: IA1_06235
SENC: SEET0819_12965
SBG: SBG_1109(aadA)
SBZ: A464_1205
SBV: N643_05265
SALZ: EOS98_13170(aadA) EOS98_23490
SFE: SFxv_1143 SFxv_4143
SFN: SFy_1440
SFS: SFyv_1489
SSN: SSON_3896(aadA)
ENL: A3UG_21725
ECLY: LI62_012770
EHM: AB284_00830
ECLS: LI67_024955
ESH: C1N69_21695
KPN: KPN_pKPN4p07059(aadA)
KPM: KPHS_p300690
KPH: KPNIH24_17325 KPNIH24_26870 KPNIH24_27460 KPNIH24_27470
KPV: KPNIH29_26630
KPW: KPNIH30_26930
KPG: KPNIH32_27930 KPNIH32_28355
KPC: KPNIH10_10970 KPNIH10_26705
KPJ: N559_5186
KPA: KPNJ1_05669 KPNJ1_05817
KPX: PMK1_ndm00221(ant1)
KPB: FH42_25795 FH42_26820
KPNE: KU54_01020 KU54_01030 KU54_01515
KPNU: LI86_15200 LI86_26840 LI86_28235 LI86_28245
KOE: A225_R1p0440 A225_R1p0760
KOK: KONIH1_31115 KONIH1_32185
KOC: AB185_00175 AB185_01225 AB185_02720 AB185_03260
KQU: AVR78_27115
EAR: CCG28765
KLW: DA718_21680
CFD: CFNIH1_06155 CFNIH1_14270
CYO: CD187_15820
CPOT: FOB25_03520
CFQ: C2U38_08315 C2U38_21215 C2U38_26810(aadA1)
CAF: AL524_13660
CIF: AL515_08750
CFAR: CI104_25625
CIR: C2U53_00295(aadA1) C2U53_23740
CIE: AN232_22170 AN232_27640(aadA) AN232_27685
CPAR: CUC49_03955
LEI: C2U54_25010(aadA1) C2U54_26545(aadA1)
LEH: C3F35_26160(aadA1)
METY: MRY16398_p20070(aadA2)
YRE: HEC60_24125(aadA1)
EBC: C2U52_00370(aadA1) C2U52_01465
SMAR: SM39_pSMC1_34(aadA)
SMW: SMWW4_v1c36970
SMAF: D781_3902
SERF: L085_10150
SRZ: AXX16_1244
SERM: CLM71_20005
SOF: NCTC11214_04436(ant1)
PANT: PSNIH1_20585
PANP: PSNIH2_21630 PSNIH2_21665
PCIB: F9282_19600(aadA1)
PSI: S70_21070
PSX: DR96_3112
PRQ: CYG50_00660 CYG50_16055(aadA1)
PVC: G3341_10330
KIN: AB182_03100
PDZ: HHA33_25990
PMP: Pmu_03420(aadA25)
AIO: EXH44_00950(aadA1)
PSU: Psesu_2826
VCQ: EN18_05755
PNC: NCGM2_1759(aadA1)
PAEB: NCGM1900_3708(aadA6)
PMK: MDS_2542
PPUH: B479_26984
PSA: PST_2171
PSZ: PSTAB_2058
PSR: PSTAA_2202
PSJ: PSJM300_03550
ACB: A1S_0131
ABM: ABSDF0145
ABY: ABAYE3570(aadA1) ABAYE3618(aadA1) ABAYE3739
ABC: ACICU_00156
ABN: AB57_0171 AB57_0293(aadA1)
ABB: ABBFA_03356(ant1)
ABX: ABK1_0164 ABK1_1143
ABZ: ABZJ_00158(ant(3'')-II) ABZJ_01289(aadA1) ABZJ_05070(aadA1)
ABR: ABTJ_01327 ABTJ_02579 ABTJ_03672
ABD: ABTW07_0156 ABTW07_3885(aadA1) ABTW07_3901(aadA1)
ABAD: ABD1_01350(aadA)
ABJ: BJAB07104_00166 BJAB07104_p0090
ABAB: BJAB0715_00178
ABAJ: BJAB0868_00173 BJAB0868_p0101
ABAZ: P795_16505
ABK: LX00_00825
ABAU: IX87_15250
ABAA: IX88_02960
ABW: BL01_01055
ABAL: ABLAC_36340
ACC: BDGL_003056(ant)
AJN: BVL33_11240
AUG: URS_0862
ADS: FPL17_13585(ant(3'')-II)
MBL: AAX09_10140
SHF: CEQ32_08445 CEQ32_19865
LPP: plpp0092
RHH: E0Z06_09360 E0Z06_15160(aadA1)
APAC: S7S_01185
AHH: RY45_02925
AAJ: BOQ57_11180 BOQ57_11320
ASA: ASA_P4G100(aadA)
AEA: C2U39_10275 C2U39_22035 C2U39_23830
AES: C2U30_02790
NBL: GJV52_06020(aadA)
BUR: Bcep18194_B2105
BCM: Bcenmc03_3549
BCJ: BCAM1013a
BCEO: I35_4932
BCED: DM42_4074
BPYR: ABD05_16735
BSEM: WJ12_25325
BSTL: BBJ41_18345
BPAR: BN117_3644(aadA4)
BPA: BPP1010(aadA4)
BBH: BN112_2235(aadA4)
BBR: BB1224(aadA4)
BBM: BN115_1180(aadA4)
BBX: BBS798_1186(aadA4)
PUS: CKA81_11630
AFA: UZ73_19160
CKE: B5M06_08275
COF: FOZ74_01865
SIMP: C6571_18320
MELA: C6568_16815(aadA1)
NST: Nstercoris_00876
NMU: Nmul_A0161
THU: AC731_003650
MXA: MXAN_1698
MSD: MYSTI_05831
MFU: LILAB_34765
MMAS: MYMAC_005253
SME: SMa2315 SMa2317
RIR: BN877_II1271(aadA)
PDE: Pden_4803
EFA: EF1076
SCO: SCO4355(SCD19.10)
NAE: BHE16_08500
SYO: C7I86_08920(aadA1)
MGOS: DIU38_018140
DIN: Selin_0013
 » show all
Reference
1  [PMID:4887506]
  Authors
Harwood JH, Smith DH.
  Title
Resistance factor-mediated streptomycin resistance.
  Journal
J Bacteriol 97:1262-71 (1969)
DOI:10.1128/JB.97.3.1262-1271.1969
Other DBs
ExplorEnz - The Enzyme Database: 2.7.7.47
IUBMB Enzyme Nomenclature: 2.7.7.47
ExPASy - ENZYME nomenclature database: 2.7.7.47
BRENDA, the Enzyme Database: 2.7.7.47
CAS: 52660-23-8
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