| Entry |
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| Name |
molybdenum cofactor cytidylyltransferase;
MocA;
CTP:molybdopterin cytidylyltransferase;
MoCo cytidylyltransferase;
Mo-MPT cytidyltransferase
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| Class |
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
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| Sysname |
CTP:molybdenum cofactor cytidylyltransferase
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| Reaction(IUBMB) |
CTP + molybdenum cofactor = diphosphate + cytidylyl molybdenum cofactor [RN: R11582]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
diphosphate [CPD: C00013];
cytidylyl molybdenum cofactor [CPD: C21485]
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| Comment |
Catalyses the cytidylation of the molybdenum cofactor. This modification occurs only in prokaryotes. Divalent cations such as Mg2+ or Mn2+ are required for activity. ATP or GTP cannot replace CTP.
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| History |
EC 2.7.7.76 created 2011
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| Pathway |
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| Orthology |
| K07141 | molybdenum cofactor cytidylyltransferase |
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| Genes |
» show all
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| Reference |
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| Authors |
Neumann M, Mittelstadt G, Seduk F, Iobbi-Nivol C, Leimkuhler S |
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| Title |
MocA is a specific cytidylyltransferase involved in molybdopterin cytosine dinucleotide biosynthesis in Escherichia coli. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Neumann M, Seduk F, Iobbi-Nivol C, Leimkuhler S |
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| Title |
Molybdopterin dinucleotide biosynthesis in Escherichia coli: identification of amino acid residues of molybdopterin dinucleotide transferases that determine specificity for binding of guanine or cytosine nucleotides. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.7.7.76 |
| ExPASy - ENZYME nomenclature database: | 2.7.7.76 |
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| LinkDB |
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