| Entry |
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| Name |
GDP-D-glucose phosphorylase
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| Class |
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
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| Sysname |
GDP:alpha-D-glucose 1-phosphate guanylyltransferase
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| Reaction(IUBMB) |
GDP-alpha-D-glucose + phosphate = alpha-D-glucose 1-phosphate + GDP [RN: R09752]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzyme may be involved in prevention of misincorporation of glucose in place of mannose residues into glycoconjugates i.e. to remove accidentally produced GDP-alpha-D-glucose. Activities with GDP-L-galactose, GDP-D-mannose and UDP-D-glucose are all less than 3% that with GDP-D-glucose.
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| History |
EC 2.7.7.78 created 2011
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| Orthology |
| K15630 | GDP-D-glucose phosphorylase |
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| Genes |
» show all
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| Reference |
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| Authors |
Adler LN, Gomez TA, Clarke SG, Linster CL |
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| Title |
A novel GDP-D-glucose phosphorylase involved in quality control of the nucleoside diphosphate sugar pool in Caenorhabditis elegans and mammals. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.7.7.78 |
| ExPASy - ENZYME nomenclature database: | 2.7.7.78 |
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| LinkDB |
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