KEGG   ENZYME: 3.2.1.206
Entry
EC 3.2.1.206                Enzyme                                 

Name
oleuropein beta-glucosidase;
OeGLU (gene name)
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
Sysname
oleuropein 2-beta-D-glucohydrolase
Reaction(IUBMB)
oleuropein + H2O = oleuropein aglycone + D-glucopyranose [RN:R11942]
Reaction(KEGG)
R11942
Substrate
oleuropein [CPD:C09794];
H2O [CPD:C00001]
Product
oleuropein aglycone [CPD:C21786];
D-glucopyranose [CPD:C00031]
Comment
Oleuropein is a glycosylated secoiridoid exclusively biosynthesized by members of the Oleaceae plant family where it is part of a defence system againt herbivores. The enzyme also hydrolyses ligstroside and demethyloleuropein.
History
EC 3.2.1.206 created 2017
Orthology
K22425  oleuropein beta-glucosidase
Genes
OEU: 111404214
Reference
1  [PMID:16349442]
  Authors
Ciafardini G, Marsilio V, Lanza B, Pozzi N
  Title
Hydrolysis of Oleuropein by Lactobacillus plantarum Strains Associated with Olive Fermentation.
  Journal
Appl Environ Microbiol 60:4142-7 (1994)
DOI:10.1128/AEM.60.11.4142-4147.1994
Reference
2  [PMID:19689134]
  Authors
Romero-Segura C, Sanz C, Perez AG
  Title
Purification and characterization of an olive fruit beta-glucosidase involved in  the biosynthesis of virgin olive oil phenolics.
  Journal
J Agric Food Chem 57:7983-8 (2009)
DOI:10.1021/jf901293c
Reference
3  [PMID:22475562]
  Authors
Gutierrez-Rosales F, Romero MP, Casanovas M, Motilva MJ, Minguez-Mosquera MI
  Title
beta-Glucosidase involvement in the formation and transformation of oleuropein during the growth and development of olive fruits (Olea europaea L. cv. Arbequina) grown under different farming practices.
  Journal
J Agric Food Chem 60:4348-58 (2012)
DOI:10.1021/jf205209y
Reference
4  [PMID:25697790]
  Authors
Koudounas K, Banilas G, Michaelidis C, Demoliou C, Rigas S, Hatzopoulos P
  Title
A defence-related Olea europaea beta-glucosidase hydrolyses and activates oleuropein into a potent protein cross-linking agent.
  Journal
J Exp Bot 66:2093-106 (2015)
DOI:10.1093/jxb/erv002
  Sequence
Reference
5  [PMID:28483880]
  Authors
Koudounas K, Thomopoulou M, Michaelidis C, Zevgiti E, Papakostas G, Tserou P, Daras G, Hatzopoulos P
  Title
The C-Domain of Oleuropein beta-Glucosidase Assists in Protein Folding and Sequesters the Enzyme in Nucleus.
  Journal
Plant Physiol 174:1371-1383 (2017)
DOI:10.1104/pp.17.00512
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.2.1.206
IUBMB Enzyme Nomenclature: 3.2.1.206
ExPASy - ENZYME nomenclature database: 3.2.1.206
BRENDA, the Enzyme Database: 3.2.1.206
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