| Entry |
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| Name |
carboxypeptidase A;
carboxypolypeptidase;
pancreatic carboxypeptidase A;
tissue carboxypeptidase A
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| Class |
Hydrolases;
Acting on peptide bonds (peptidases);
Metallocarboxypeptidases
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| Reaction(IUBMB) |
Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro
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| Comment |
A zinc enzyme formed from procarboxypeptidase A. Isolated from cattle, pig and dogfish pancreas, and other sources including mast cells [3] and skeletal muscle [4]. Type example of peptidase family M14.
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| History |
EC 3.4.17.1 created 1961 as EC 3.4.2.1, transferred 1972 to EC 3.4.12.2, transferred 1978 to EC 3.4.17.1
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| Orthology |
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| Genes |
» show all
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| Reference |
1 |
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| Authors |
Petra, P.H. |
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| Title |
Bovine procarboxypeptidase and carboxypeptidase A. |
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| Journal |
Methods Enzymol 19:460-503 (1970) |
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| Reference |
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| Authors |
Reeck GR, Walsh KA, Neurath H. |
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| Title |
Isolation and characterization of carboxypeptidases A and B from activated pancreatic juice. |
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| Journal |
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| Reference |
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| Authors |
Everitt MT, Neurath H. |
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| Title |
Rat peritoneal mast cell carboxypeptidase: localization, purification, and enzymatic properties. |
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| Journal |
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| Reference |
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| Authors |
Bodwell JE, Meyer WL. |
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| Title |
Purification and characterization of carboxypeptidase A from rat skeletal muscle. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.4.17.1 |
| ExPASy - ENZYME nomenclature database: | 3.4.17.1 |
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| LinkDB |
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