KEGG   ENZYME: 3.8.1.3
Entry
EC 3.8.1.3                  Enzyme                                 

Name
haloacetate dehalogenase;
monohaloacetate dehalogenase
Class
Hydrolases;
Acting on halide bonds;
In carbon-halide compounds
Sysname
haloacetate halidohydrolase
Reaction(IUBMB)
haloacetate + H2O = glycolate + halide [RN:R02336]
Reaction(KEGG)
R02336 > R02857 R05287
Substrate
haloacetate [CPD:C01812];
H2O [CPD:C00001]
Product
glycolate [CPD:C00160];
halide [CPD:C00462]
History
EC 3.8.1.3 created 1972
Pathway
ec00361  Chlorocyclohexane and chlorobenzene degradation
ec00625  Chloroalkane and chloroalkene degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K01561  haloacetate dehalogenase
Genes
STM: STM0332
SEO: STM14_0388
SEV: STMMW_04021
SEY: SL1344_0327
SEM: STMDT12_C03960
SEJ: STMUK_0338
SEB: STM474_0347
SEF: UMN798_0366
SETU: STU288_12735
SETC: CFSAN001921_15375
SENI: CY43_01985
SEI: SPC_0343
SEC: SCH_0377(deh)
SENS: Q786_01635
SED: SeD_A0364
SEG: SG0342
SEL: SPUL_2641
SET: SEN0315
SENA: AU38_01605
SENO: AU37_01600
SENV: AU39_01605
SENQ: AU40_01810
SENL: IY59_01640
SEEP: I137_12015
SENB: BN855_3240(deh)
SENE: IA1_01805
CLAP: NCTC11466_02285(dehH1)
PSTS: E05_05560
SOF: NCTC11214_04587(dehH1)
RAA: Q7S_06690
EBI: EbC_06280
LRI: NCTC12151_03420(dehH1)
PAE: PA2086
PAEV: N297_2151
PAEI: N296_2151
PAEP: PA1S_15250
PAEM: U769_14850
PAEL: T223_16530
PAEG: AI22_18520
PAEC: M802_2148
PAEO: M801_2150
PFL: PFL_4714
PFS: PFLU_2052
PFB: VO64_1364
PSTT: CH92_06685
PSES: PSCI_1385(dehH1)
PANR: A7J50_2054
PIN: Ping_2087
GAI: IMCC3135_09085(dehH1)
CSA: Csal_2775
HAM: HALO1210
RSO: RSc0256(dehH)
RSC: RCFBP_21237(dehH)
RSL: RPSI07_3158(dehH)
RSM: CMR15_30691(dehH) CMR15_mp10103(dehH)
RSE: F504_273
RPI: Rpic_0098
REH: H16_A0197(h16_A0197)
CNC: CNE_1c01870(dehH)
RME: Rmet_0129(dehH2) Rmet_0202(dehH1)
CTI: RALTA_A0140(dehH)
CGD: CR3_1253(dehH)
BPS: BPSL0329
BPM: BURPS1710b_0537(dehH)
BPSE: BDL_1653
BPSM: BBQ_3095
BPSU: BBN_3218
BPSD: BBX_43
BPK: BBK_1135
BPSH: DR55_757
BPSA: BBU_1810
BPSO: X996_377
BUT: X994_2367
BTE: BTH_I0308
BTQ: BTQ_330
BTJ: BTJ_2156
BTZ: BTL_64
BTD: BTI_3401
BTV: BTHA_124
BTHE: BTN_1321
BTHM: BTRA_271
BTHA: DR62_1502
BTHL: BG87_234
BCEN: DM39_3060
BCEW: DM40_564
BMU: Bmul_2960
BMK: DM80_1959
BMUL: NP80_3087
BCT: GEM_0476
BCON: NL30_27915
BUB: BW23_1919
BLAT: WK25_14355
BTEI: WS51_25150
BSEM: WJ12_14875
BPSL: WS57_33625
BMEC: WJ16_15050
BSTG: WT74_15650
BGU: KS03_722
BUL: BW21_3551
BXE: Bxe_A4275
BXB: DR64_1953
BPH: Bphy_0158
PNU: Pnuc_0983
PSPU: NA29_17245
CABA: SBC2_01640 SBC2_70470(dehH1)
BPT: Bpet4772
AXX: ERS451415_05979(dehH1)
PUT: PT7_2315
AMIM: MIM_c40530
ODI: ODI_R3533
PNA: Pnap_1631
ACRA: BSY15_1100
DAC: Daci_4283
CTES: O987_20135
MPT: Mpe_A3619
HAR: HEAR0772(dehH)
MMS: mma_2342
JAG: GJA_2340(dehH1)
CARE: LT85_2416
LCH: Lcho_3194
RDP: RD2015_41
PBH: AAW51_0642(dehH) AAW51_2052(dehH)
DAR: Daro_3835
AZO: azo0046(dehH)
AOA: dqs_0056
BPRC: D521_0819
AELL: AELL_1887
APAI: APAC_1605
HEBR: AEBR_0724
PACO: AACT_1223
SMUL: SMUL_1262
SHAL: SHALO_1243
SULJ: SJPD1_1268
MHUA: MCHK_3370
RLG: Rleg_5106
RHT: NT26_0709
NEN: NCHU2750_42780(dehH)
OAN: Oant_3595
OAH: DR92_2891
BRA: BRADO6083
BRAD: BF49_3030
RPA: RPA1163
RPB: RPB_1864
RPD: RPD_4103
RPT: Rpal_1354
XAU: Xaut_3097
AZC: AZC_2387
SNO: Snov_1594
MDI: METDI4852
MEX: Mext_3868
MCH: Mchl_4177
MPO: Mpop_4324
MET: M446_6061
MOR: MOC_2053
META: Y590_19025
MAQU: Maq22A_c19895(mhpC)
MSL: Msil_3226
MSC: BN69_2234
HDI: HDIA_1096
JAN: Jann_4032
RDE: RD1_2829(dehH1)
RLI: RLO149_c016110(dehH)
DSH: Dshi_2992(dehH)
OAT: OAN307_c38750(dehH)
LAQU: R2C4_06785
PTP: RCA23_c28880(dehH)
RHC: RGUI_2701
SPSE: SULPSESMR1_01227(dehH1)
ROH: FIU89_08425(dehH2)
ROT: FIV09_11265(dehH1)
MALU: KU6B_07070
SMAZ: LH19_04490
SPHU: SPPYR_0652
SECH: B18_22330
SPHT: K426_10825
ACR: Acry_0535
GDI: GDI1890
GDJ: Gdia_0113
GXY: GLX_29910
KSC: CD178_03291(dehH1)
APK: APA386B_1P230(deh)
SHUM: STHU_27960
TMO: TMO_1621
BAO: BAMF_0507
BQL: LL3_00540
BAMI: KSO_016705
BCL: ABC3436
PFAC: PFJ30894_01307(dehH1)
RER: RER_57030
REY: O5Y_27250
RRT: 4535765_02533(fac-dex)
SCO: SCO0899(SCM1.32) SCO7205(SC2H12.04)
SALB: XNR_3267
SGR: SGR_6681
SFA: Sfla_1473
STRP: F750_5400
SALL: SAZ_32535
SPRI: SPRI_4444
SRW: TUE45_pSRc_0178(TUE45_pSRTUE45c_0178)
SLE: sle_06290(sle_06290)
STRD: NI25_03090
SFK: KY5_4406c
AAU: AAur_3749
KRH: KRH_23010
CFL: Cfla_0503
NML: Namu_5068
GOB: Gobs_3414
MMAR: MODMU_2017(dehH)
PSEE: FRP1_20015
PSEH: XF36_03790
AMI: Amir_6167
KAL: KALB_4787
ACTI: UA75_26820
ACAD: UA74_26235
ACTN: L083_4527
CAI: Caci_6541
CWO: Cwoe_2166
MAR: MAE_40040
MPK: VL20_2811
CYT: cce_0529
ANA: alr0039
AVA: Ava_2640
RCA: Rcas_1001
CAU: Caur_0773
CAG: Cagg_2835
ABAS: ACPOL_0725
SSO: SSO1159
 » show all
Reference
1  [PMID:14321384]
  Authors
GOLDMAN P.
  Title
THE ENZYMATIC CLEAVAGE OF THE CARBON-FLUORINE BOND IN FLUOROACETATE.
  Journal
J Biol Chem 240:3434-8 (1965)
Reference
2  [PMID:5928195]
  Authors
Goldman P, Milne GW.
  Title
Carbon-fluorine bond cleavage. II. Studies on the mechanism of the defluorination of fluoroacetate.
  Journal
J Biol Chem 241:5557-9 (1966)
Other DBs
ExplorEnz - The Enzyme Database: 3.8.1.3
IUBMB Enzyme Nomenclature: 3.8.1.3
ExPASy - ENZYME nomenclature database: 3.8.1.3
UM-BBD (Biocatalysis/Biodegradation Database): 3.8.1.3
BRENDA, the Enzyme Database: 3.8.1.3
CAS: 37289-40-0
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