Entry
Name
trans-aconitate decarboxylase;
TAD1 (gene name)
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname
trans-aconitate carboxy-lyase (itaconate-forming)
Reaction(IUBMB)
trans-aconitate = itaconate + CO2 [RN:
R11749 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme, characterized from the smut fungus Ustilago maydis, is involved in an alternative pathway for the biosynthesis of itaconate. cf. EC
4.1.1.6 , cis-aconitate decarboxylase.
History
EC 4.1.1.113 created 2018
Pathway
ec00660 C5-Branched dibasic acid metabolism
Orthology
K22004 trans-aconitate decarboxylase
Genes
Taxonomy
Reference
Authors
Geiser E, Przybilla SK, Friedrich A, Buckel W, Wierckx N, Blank LM, Bolker M
Title
Ustilago maydis produces itaconic acid via the unusual intermediate trans-aconitate.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 4.1.1.113
LinkDB
All DBs